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Enterococcal endocarditis: 107 cases from the international collaboration on endocarditis merged database.

Publication ,  Journal Article
McDonald, JR; Olaison, L; Anderson, DJ; Hoen, B; Miro, JM; Eykyn, S; Abrutyn, E; Fowler, VG; Habib, G; Selton-Suty, C; Pappas, PA; Cabell, CH ...
Published in: Am J Med
July 2005

PURPOSE: To describe clinical features and outcomes of enterococcal left-sided native valve endocarditis and to compare it to endocarditis caused by other pathogens. SUBJECTS AND METHODS: Patients in the International Collaboration on Endocarditis-Merged Database were included if they had left-sided native valve endocarditis. Demographic characteristics, clinical features, and outcomes were analyzed. Multivariable analysis evaluated enterococcus as a predictor of mortality. RESULTS: Of 1285 patients with left-sided native valve endocarditis, 107 had enterococcal endocarditis. Enterococcal endocarditis was most frequently seen in elderly men, frequently involved the aortic valve, tended to produce heart failure rather than embolic events, and had relatively low short-term mortality. Compared to patients with non-enterococcal endocarditis, patients with enterococcal endocarditis had similar rates of nosocomial acquisition, heart failure, embolization, surgery, and mortality. Compared to patients with streptococcal endocarditis, patients with enterococcal endocarditis were more likely to be nosocomially acquired (9 of 59 [15%] vs 2 of 400 [1%]; P <.0001) and have heart failure (49 of 107 [46%] vs 234 of 666 [35%]; P = 0.03). Compared to patients with S. aureus endocarditis, patients with enterococcal endocarditis were less likely to embolize (28 of 107 [26%] vs 155 of 314 [49%]; P <.0001) and less likely to die (12 of 107 [11%] vs 83 of 313 [27%]; P = 0.001). Multivariable analysis of all patients with left-sided native valve endocarditis showed that enterococcal endocarditis was associated with lower mortality (odds ratio [OR] 0.49; 95% confidence interval [CI] 0.24 to 0.97). CONCLUSIONS: Enterococcal native valve endocarditis has a distinctive clinical picture with a good prognosis.

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Published In

Am J Med

DOI

ISSN

0002-9343

Publication Date

July 2005

Volume

118

Issue

7

Start / End Page

759 / 766

Location

United States

Related Subject Headings

  • United States
  • Tricuspid Valve
  • Survival Rate
  • Streptococcus
  • Streptococcal Infections
  • Severity of Illness Index
  • Pulmonary Valve
  • Prognosis
  • Middle Aged
  • Male
 

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McDonald, J. R., Olaison, L., Anderson, D. J., Hoen, B., Miro, J. M., Eykyn, S., … Sexton, D. J. (2005). Enterococcal endocarditis: 107 cases from the international collaboration on endocarditis merged database. Am J Med, 118(7), 759–766. https://doi.org/10.1016/j.amjmed.2005.02.020
McDonald, J. R., L. Olaison, D. J. Anderson, B. Hoen, J. M. Miro, S. Eykyn, E. Abrutyn, et al. “Enterococcal endocarditis: 107 cases from the international collaboration on endocarditis merged database.Am J Med 118, no. 7 (July 2005): 759–66. https://doi.org/10.1016/j.amjmed.2005.02.020.
McDonald JR, Olaison L, Anderson DJ, Hoen B, Miro JM, Eykyn S, et al. Enterococcal endocarditis: 107 cases from the international collaboration on endocarditis merged database. Am J Med. 2005 Jul;118(7):759–66.
McDonald, J. R., et al. “Enterococcal endocarditis: 107 cases from the international collaboration on endocarditis merged database.Am J Med, vol. 118, no. 7, July 2005, pp. 759–66. Pubmed, doi:10.1016/j.amjmed.2005.02.020.
McDonald JR, Olaison L, Anderson DJ, Hoen B, Miro JM, Eykyn S, Abrutyn E, Fowler VG, Habib G, Selton-Suty C, Pappas PA, Cabell CH, Corey GR, Marco F, Sexton DJ. Enterococcal endocarditis: 107 cases from the international collaboration on endocarditis merged database. Am J Med. 2005 Jul;118(7):759–766.
Journal cover image

Published In

Am J Med

DOI

ISSN

0002-9343

Publication Date

July 2005

Volume

118

Issue

7

Start / End Page

759 / 766

Location

United States

Related Subject Headings

  • United States
  • Tricuspid Valve
  • Survival Rate
  • Streptococcus
  • Streptococcal Infections
  • Severity of Illness Index
  • Pulmonary Valve
  • Prognosis
  • Middle Aged
  • Male