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Enterococcal prosthetic valve infective endocarditis: report of 45 episodes from the International Collaboration on Endocarditis-merged database.

Publication ,  Journal Article
Anderson, DJ; Olaison, L; McDonald, JR; Miro, JM; Hoen, B; Selton-Suty, C; Doco-Lecompte, T; Abrutyn, E; Habib, G; Eykyn, S; Pappas, PA ...
Published in: Eur J Clin Microbiol Infect Dis
October 2005

Enterococcal prosthetic valve infective endocarditis (PVE) is an incompletely understood disease. In the present study, patients with enterococcal PVE were compared to patients with enterococcal native valve endocarditis (NVE) and other types of PVE to determine differences in basic clinical characteristics and outcomes using a large multicenter, international database of patients with definite endocarditis. Forty-five of 159 (29%) cases of definite enterococcal endocarditis were PVE. Patients with enterococcal PVE were demographically similar to patients with enterococcal NVE but had more intracardiac abscesses (20% vs. 6%; p=0.009), fewer valve vegetations (51% vs. 79%; p<0.001), and fewer cases of new valvular regurgitation (12% vs. 45%; p=0.01). Patients with either enterococcal PVE or NVE were elderly (median age, 73 vs. 69; p=0.06). Rates of in-hospital mortality, surgical intervention, heart failure, peripheral embolization, and stroke were similar in both groups. Patients with enterococcal PVE were also demographically similar to patients with other types of PVE, but mortality may be lower (14% vs. 26%; p=0.08). Notably, 93% of patients with enterococcal PVE came from European centers, as compared with only 79% of patients with enterococcal NVE (p=0.03). Thus, patients with enterococcal PVE have higher rates of myocardial abscess formation and lower rates of new regurgitation compared to patients with enterococcal NVE, but there are no differences between the groups with regard to surgical or mortality rates. In contrast, though patients with enterococcal PVE and patients with other types of PVE share similar characteristics, mortality is higher in the latter group. Importantly, the prevalence of enterococcal PVE was higher in the European centers in this study.

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Published In

Eur J Clin Microbiol Infect Dis

DOI

ISSN

0934-9723

Publication Date

October 2005

Volume

24

Issue

10

Start / End Page

665 / 670

Location

Germany

Related Subject Headings

  • Prosthesis-Related Infections
  • Middle Aged
  • Microbiology
  • Male
  • International Cooperation
  • Humans
  • Heart Valves
  • Heart Valve Prosthesis
  • Gram-Positive Bacterial Infections
  • Female
 

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Anderson, D. J., Olaison, L., McDonald, J. R., Miro, J. M., Hoen, B., Selton-Suty, C., … Cabell, C. H. (2005). Enterococcal prosthetic valve infective endocarditis: report of 45 episodes from the International Collaboration on Endocarditis-merged database. Eur J Clin Microbiol Infect Dis, 24(10), 665–670. https://doi.org/10.1007/s10096-005-0007-9
Anderson, D. J., L. Olaison, J. R. McDonald, J. M. Miro, B. Hoen, C. Selton-Suty, T. Doco-Lecompte, et al. “Enterococcal prosthetic valve infective endocarditis: report of 45 episodes from the International Collaboration on Endocarditis-merged database.Eur J Clin Microbiol Infect Dis 24, no. 10 (October 2005): 665–70. https://doi.org/10.1007/s10096-005-0007-9.
Anderson DJ, Olaison L, McDonald JR, Miro JM, Hoen B, Selton-Suty C, et al. Enterococcal prosthetic valve infective endocarditis: report of 45 episodes from the International Collaboration on Endocarditis-merged database. Eur J Clin Microbiol Infect Dis. 2005 Oct;24(10):665–70.
Anderson, D. J., et al. “Enterococcal prosthetic valve infective endocarditis: report of 45 episodes from the International Collaboration on Endocarditis-merged database.Eur J Clin Microbiol Infect Dis, vol. 24, no. 10, Oct. 2005, pp. 665–70. Pubmed, doi:10.1007/s10096-005-0007-9.
Anderson DJ, Olaison L, McDonald JR, Miro JM, Hoen B, Selton-Suty C, Doco-Lecompte T, Abrutyn E, Habib G, Eykyn S, Pappas PA, Fowler VG, Sexton DJ, Almela M, Corey GR, Cabell CH. Enterococcal prosthetic valve infective endocarditis: report of 45 episodes from the International Collaboration on Endocarditis-merged database. Eur J Clin Microbiol Infect Dis. 2005 Oct;24(10):665–670.
Journal cover image

Published In

Eur J Clin Microbiol Infect Dis

DOI

ISSN

0934-9723

Publication Date

October 2005

Volume

24

Issue

10

Start / End Page

665 / 670

Location

Germany

Related Subject Headings

  • Prosthesis-Related Infections
  • Middle Aged
  • Microbiology
  • Male
  • International Cooperation
  • Humans
  • Heart Valves
  • Heart Valve Prosthesis
  • Gram-Positive Bacterial Infections
  • Female