Risk factors for pediatric ventriculoperitoneal shunt infection and predictors of infectious pathogens.

Published

Journal Article

Identification of risk factors for shunt infection and predictors of infectious pathogens may improve current methods to prevent and treat shunt infections. We reviewed data on 820 consecutive ventriculoperitoneal (VP) shunt placement procedures in 442 pediatric patients at our institution during 1992-1998. Ninety-two shunts (11%) developed infection a median of 19 days (interquartile range, 11-35 days) after insertion. Premature birth (relative risk [RR], 4.81; 95% confidence interval [CI], 2.19-10.87), previous shunt infection (RR, 3.83; 95% CI, 2.40-6.13), and intraoperative use of the neuroendoscope (RR, 1.58; 95% CI, 1.01-2.50) were independent risk factors for shunt infection. The bacterial organisms early after shunt surgery (<14 days) were the same as those late after shunt surgery (>14 days). As determined by an analysis of the 92 infected shunts, hospital stay of >3 days at the time of shunt insertion (odds ratio [OR], 5.27; 95% CI, 1.15-25.3) and prior Staphylococcus aureus shunt infection (OR, 5.91; 95% CI, 1.35-25.9) independently increased the odds that S. aureus was the causal pathogen.

Full Text

Duke Authors

Cited Authors

  • McGirt, MJ; Zaas, A; Fuchs, HE; George, TM; Kaye, K; Sexton, DJ

Published Date

  • April 1, 2003

Published In

Volume / Issue

  • 36 / 7

Start / End Page

  • 858 - 862

PubMed ID

  • 12652386

Pubmed Central ID

  • 12652386

Electronic International Standard Serial Number (EISSN)

  • 1537-6591

Digital Object Identifier (DOI)

  • 10.1086/368191

Language

  • eng

Conference Location

  • United States