Skip to main content
Journal cover image

Recurrent Staphylococcus aureus bacteremia: pulsed-field gel electrophoresis findings in 29 patients.

Publication ,  Journal Article
Fowler, VG; Kong, LK; Corey, GR; Gottlieb, GS; McClelland, RS; Sexton, DJ; Gesty-Palmer, D; Harrell, LJ
Published in: J Infect Dis
May 1999

To identify risk factors for relapse among 309 prospectively identified cases of Staphylococcus aureus bacteremia, patients with recurrent S. aureus bacteremia were identified, and pulsed-field gel electrophoresis (PFGE) was performed on isolates from both episodes. PFGE banding patterns from both isolates were identical in 23 patients, consistent with relapsed infection. Patients with PFGE-confirmed relapse were more likely by both univariate and multivariate analyses to have an indwelling foreign body (odds ratio [OR]=18.2, 95% confidence interval [CI]=7. 6-43.6; P<.001), to have received vancomycin therapy (OR=4.1, 95% CI=1.5-11.6; P=.008), or be hemodialysis-dependent (OR=4.1, 95% CI=1. 8-9.3; P=.002) than patients who did not develop recurrent bacteremia. These results suggest that recurrent episodes of S. aureus bacteremia are primarily relapses and are associated with an indwelling foreign body, receiving vancomycin therapy, and hemodialysis dependence.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Infect Dis

DOI

ISSN

0022-1899

Publication Date

May 1999

Volume

179

Issue

5

Start / End Page

1157 / 1161

Location

United States

Related Subject Headings

  • Staphylococcus aureus
  • Staphylococcal Infections
  • Risk Factors
  • Recurrence
  • Prospective Studies
  • Middle Aged
  • Microbiology
  • Male
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Fowler, V. G., Kong, L. K., Corey, G. R., Gottlieb, G. S., McClelland, R. S., Sexton, D. J., … Harrell, L. J. (1999). Recurrent Staphylococcus aureus bacteremia: pulsed-field gel electrophoresis findings in 29 patients. J Infect Dis, 179(5), 1157–1161. https://doi.org/10.1086/314712
Fowler, V. G., L. K. Kong, G. R. Corey, G. S. Gottlieb, R. S. McClelland, D. J. Sexton, D. Gesty-Palmer, and L. J. Harrell. “Recurrent Staphylococcus aureus bacteremia: pulsed-field gel electrophoresis findings in 29 patients.J Infect Dis 179, no. 5 (May 1999): 1157–61. https://doi.org/10.1086/314712.
Fowler VG, Kong LK, Corey GR, Gottlieb GS, McClelland RS, Sexton DJ, et al. Recurrent Staphylococcus aureus bacteremia: pulsed-field gel electrophoresis findings in 29 patients. J Infect Dis. 1999 May;179(5):1157–61.
Fowler, V. G., et al. “Recurrent Staphylococcus aureus bacteremia: pulsed-field gel electrophoresis findings in 29 patients.J Infect Dis, vol. 179, no. 5, May 1999, pp. 1157–61. Pubmed, doi:10.1086/314712.
Fowler VG, Kong LK, Corey GR, Gottlieb GS, McClelland RS, Sexton DJ, Gesty-Palmer D, Harrell LJ. Recurrent Staphylococcus aureus bacteremia: pulsed-field gel electrophoresis findings in 29 patients. J Infect Dis. 1999 May;179(5):1157–1161.
Journal cover image

Published In

J Infect Dis

DOI

ISSN

0022-1899

Publication Date

May 1999

Volume

179

Issue

5

Start / End Page

1157 / 1161

Location

United States

Related Subject Headings

  • Staphylococcus aureus
  • Staphylococcal Infections
  • Risk Factors
  • Recurrence
  • Prospective Studies
  • Middle Aged
  • Microbiology
  • Male
  • Humans
  • Female