Survey of US public attitudes toward pharmacogenetic testing.

Journal Article (Journal Article)

To assess public attitudes and interest in pharmacogenetic (PGx) testing, we conducted a random-digit-dial telephone survey of US adults, achieving a response rate of 42% (n=1139). Most respondents expressed interest in PGx testing to predict mild or serious side effects (73±3.29 and 85±2.91%, respectively), guide dosing (91%) and assist with drug selection (92%). Younger individuals (aged 18-34 years) were more likely to be interested in PGx testing to predict serious side effects (vs aged 55+ years), as well as Whites, those with a college degree, and who had experienced side effects from medications. However, most respondents (78±3.14%) were not likely to have a PGx test if there was a risk that their DNA sample or test result could be shared without their permission. Given differences in interest among some groups, providers should clearly discuss the purpose of testing, alternative testing options (if available) and policies to protect patient privacy and confidentiality.

Full Text

Duke Authors

Cited Authors

  • Haga, SB; O'Daniel, JM; Tindall, GM; Lipkus, IR; Agans, R

Published Date

  • June 2012

Published In

Volume / Issue

  • 12 / 3

Start / End Page

  • 197 - 204

PubMed ID

  • 21321582

Pubmed Central ID

  • PMC3139751

Electronic International Standard Serial Number (EISSN)

  • 1473-1150

Digital Object Identifier (DOI)

  • 10.1038/tpj.2011.1


  • eng

Conference Location

  • United States