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Sparsity based denoising of spectral domain optical coherence tomography images.

Publication ,  Journal Article
Fang, L; Li, S; Nie, Q; Izatt, JA; Toth, CA; Farsiu, S
Published in: Biomed Opt Express
May 1, 2012

In this paper, we make contact with the field of compressive sensing and present a development and generalization of tools and results for reconstructing irregularly sampled tomographic data. In particular, we focus on denoising Spectral-Domain Optical Coherence Tomography (SDOCT) volumetric data. We take advantage of customized scanning patterns, in which, a selected number of B-scans are imaged at higher signal-to-noise ratio (SNR). We learn a sparse representation dictionary for each of these high-SNR images, and utilize such dictionaries to denoise the low-SNR B-scans. We name this method multiscale sparsity based tomographic denoising (MSBTD). We show the qualitative and quantitative superiority of the MSBTD algorithm compared to popular denoising algorithms on images from normal and age-related macular degeneration eyes of a multi-center clinical trial. We have made the corresponding data set and software freely available online.

Duke Scholars

Published In

Biomed Opt Express

DOI

EISSN

2156-7085

Publication Date

May 1, 2012

Volume

3

Issue

5

Start / End Page

927 / 942

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Fang, L., Li, S., Nie, Q., Izatt, J. A., Toth, C. A., & Farsiu, S. (2012). Sparsity based denoising of spectral domain optical coherence tomography images. Biomed Opt Express, 3(5), 927–942. https://doi.org/10.1364/BOE.3.000927
Fang, Leyuan, Shutao Li, Qing Nie, Joseph A. Izatt, Cynthia A. Toth, and Sina Farsiu. “Sparsity based denoising of spectral domain optical coherence tomography images.Biomed Opt Express 3, no. 5 (May 1, 2012): 927–42. https://doi.org/10.1364/BOE.3.000927.
Fang L, Li S, Nie Q, Izatt JA, Toth CA, Farsiu S. Sparsity based denoising of spectral domain optical coherence tomography images. Biomed Opt Express. 2012 May 1;3(5):927–42.
Fang, Leyuan, et al. “Sparsity based denoising of spectral domain optical coherence tomography images.Biomed Opt Express, vol. 3, no. 5, May 2012, pp. 927–42. Pubmed, doi:10.1364/BOE.3.000927.
Fang L, Li S, Nie Q, Izatt JA, Toth CA, Farsiu S. Sparsity based denoising of spectral domain optical coherence tomography images. Biomed Opt Express. 2012 May 1;3(5):927–942.
Journal cover image

Published In

Biomed Opt Express

DOI

EISSN

2156-7085

Publication Date

May 1, 2012

Volume

3

Issue

5

Start / End Page

927 / 942

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics