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Risk factors for mesh/suture erosion following sacral colpopexy.

Publication ,  Journal Article
Cundiff, GW; Varner, E; Visco, AG; Zyczynski, HM; Nager, CW; Norton, PA; Schaffer, J; Brown, MB; Brubaker, L; Pelvic Floor Disorders Network,
Published in: Am J Obstet Gynecol
December 2008

OBJECTIVE: The purpose of this study was to identify risks for mesh/suture erosions following abdominal sacral colpopexy (ASC). STUDY DESIGN: We analyzed demographic, perioperative variables, and erosion status in 322 participants in the Colpopexy and Urinary Reduction Efforts study 2 years after sacral colpopexy. RESULTS: The predominant graft used was synthetic mesh: woven polyester (Mersilene; Ethicon, Inc, Somerville, NJ) (42%) or polypropylene (48%). Twenty subjects (6%) experienced mesh/suture erosion. Unadjusted risk factors for mesh/suture erosion were expanded polytrafluroethylene (ePTFE) mesh (ePTFE 4/21 [19%] vs non-ePTFE 16/301 [5%]; odds ratio [OR], 4.2), concurrent hysterectomy (OR, 4.9), and current smoking (OR, 5.2). Of those with mesh erosion, most affected women (13/17) underwent at least 1 surgery for partial or total mesh removal. Two were completely resolved, 6 had persistent problems, and 5 were lost to follow-up. No resolution was documented in the 4 women who elected observation. CONCLUSION: Expanded PTFE mesh should not be used for sacral colpopexy. Concurrent hysterectomy and smoking are modifiable risks for mesh/suture erosion.

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Published In

Am J Obstet Gynecol

DOI

EISSN

1097-6868

Publication Date

December 2008

Volume

199

Issue

6

Start / End Page

688.e1 / 688.e5

Location

United States

Related Subject Headings

  • Uterine Prolapse
  • Urinary Incontinence, Stress
  • Sutures
  • Surgical Mesh
  • Severity of Illness Index
  • Risk Factors
  • Reoperation
  • Prosthesis Failure
  • Prosthesis Design
  • Obstetrics & Reproductive Medicine
 

Citation

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Cundiff, G. W., Varner, E., Visco, A. G., Zyczynski, H. M., Nager, C. W., Norton, P. A., … Pelvic Floor Disorders Network, . (2008). Risk factors for mesh/suture erosion following sacral colpopexy. Am J Obstet Gynecol, 199(6), 688.e1-688.e5. https://doi.org/10.1016/j.ajog.2008.07.029
Cundiff, Geoffrey W., Edward Varner, Anthony G. Visco, Halina M. Zyczynski, Charles W. Nager, Peggy A. Norton, Joseph Schaffer, Morton B. Brown, Linda Brubaker, and Linda Pelvic Floor Disorders Network. “Risk factors for mesh/suture erosion following sacral colpopexy.Am J Obstet Gynecol 199, no. 6 (December 2008): 688.e1-688.e5. https://doi.org/10.1016/j.ajog.2008.07.029.
Cundiff GW, Varner E, Visco AG, Zyczynski HM, Nager CW, Norton PA, et al. Risk factors for mesh/suture erosion following sacral colpopexy. Am J Obstet Gynecol. 2008 Dec;199(6):688.e1-688.e5.
Cundiff, Geoffrey W., et al. “Risk factors for mesh/suture erosion following sacral colpopexy.Am J Obstet Gynecol, vol. 199, no. 6, Dec. 2008, pp. 688.e1-688.e5. Pubmed, doi:10.1016/j.ajog.2008.07.029.
Cundiff GW, Varner E, Visco AG, Zyczynski HM, Nager CW, Norton PA, Schaffer J, Brown MB, Brubaker L, Pelvic Floor Disorders Network. Risk factors for mesh/suture erosion following sacral colpopexy. Am J Obstet Gynecol. 2008 Dec;199(6):688.e1-688.e5.
Journal cover image

Published In

Am J Obstet Gynecol

DOI

EISSN

1097-6868

Publication Date

December 2008

Volume

199

Issue

6

Start / End Page

688.e1 / 688.e5

Location

United States

Related Subject Headings

  • Uterine Prolapse
  • Urinary Incontinence, Stress
  • Sutures
  • Surgical Mesh
  • Severity of Illness Index
  • Risk Factors
  • Reoperation
  • Prosthesis Failure
  • Prosthesis Design
  • Obstetrics & Reproductive Medicine