Timing in the baby brain.

Published

Journal Article

Ten-month-old infants and adults were tested in an auditory oddball paradigm in which 50-ms tones were separated by 1500 ms (standard interval) and occasionally 500 ms (deviant interval). Both infants and adults showed marked brain responses to the tone that followed a deviant inter-stimulus interval (ISI). Specifically, the timing-deviance event-related-potential (ERP) difference waves (deviant-ISI ERP minus standard-ISI ERP) yielded a significant, fronto-centrally distributed, mismatch negativity (MMN) in the latency range of 120-240 ms post-stimulus for infants and 110-210 ms for adults. A robust, longer latency, deviance-related positivity was also obtained for infants (330-520 ms), with a much smaller and later deviance-related positivity observed for adults (585-705 ms). These results suggest that the 10-month-old infant brain has already developed some of the same mechanisms as adults for detecting deviations in the timing of stimulus events.

Full Text

Duke Authors

Cited Authors

  • Brannon, EM; Roussel, LW; Meck, WH; Woldorff, M

Published Date

  • October 2004

Published In

Volume / Issue

  • 21 / 2

Start / End Page

  • 227 - 233

PubMed ID

  • 15464354

Pubmed Central ID

  • 15464354

International Standard Serial Number (ISSN)

  • 0926-6410

Digital Object Identifier (DOI)

  • 10.1016/j.cogbrainres.2004.04.007

Language

  • eng