Fourth ventricular schwannoma: identical clinicopathologic features as schwann cell-derived schwannoma with unique etiopathologic origins.


Journal Article

Background. To our knowledge, this is the sixth reported case in the literature of fourth ventricular schwannoma. The etiology and natural history of intraventricular schwannomas is not well understood. A thorough review of potential etiopathogenic mechanisms is provided in this case report. Case Description. A 69-year-old man presented with an incidentally found fourth ventricular tumor during an evaluation for generalized weakness, gait instability, and memory disturbance. Magnetic resonance imaging (MRI) revealed a heterogeneously enhancing lesion in the fourth ventricle. A suboccipital craniotomy was performed to resect the lesion. Histopathological examination confirmed the diagnosis of schwannoma (WHO grade I). Conclusions. Schwannomas should be considered in the differential diagnosis of intraventricular tumors. Although the embryologic origins may be different from nerve sheath-derived schwannomas, the histologic, clinical, and natural history appear identical and thus should be managed similarly.

Full Text

Duke Authors

Cited Authors

  • Hodges, TR; Karikari, IO; Nimjee, SM; Tibaleka, J; Cummings, TJ; Radhakrishnan, S; Friedman, AH

Published Date

  • 2011

Published In

Volume / Issue

  • 2011 /

Start / End Page

  • 165954 -

PubMed ID

  • 22194753

Pubmed Central ID

  • 22194753

Electronic International Standard Serial Number (EISSN)

  • 1687-9635

Digital Object Identifier (DOI)

  • 10.1155/2011/165954


  • eng

Conference Location

  • United States