p63 expression profile in normal and malignant prostate epithelial cells.
Publication
, Journal Article
Davis, LD; Zhang, W; Merseburger, A; Young, D; Xu, L; Rhim, JS; Moul, JW; Srivastava, S; Sesterhenn, IA
Published in: Anticancer Res
2002
p63 expression was evaluated in a tissue microarray of prostate tissues including benign glands, prostatic intraepithelial neoplasia and prostatic carcinoma. Immunostaining with anti-p63 antibody was restricted to basal cell nuclei. Detectable p63 was found in immortalized and early passage cell cultures, but not in senescent cultures or metastatic tumor-derived cell lines. The selective presence of p63 in basal cells of the prostate suggests that p63 can be used as a marker of basal cells and in vitro typing cell cultures of prostate cancer (CaP). The basal cell association underscores its critical functions in the biology of basal cells.
Duke Scholars
Published In
Anticancer Res
ISSN
0250-7005
Publication Date
2002
Volume
22
Issue
6C
Start / End Page
3819 / 3825
Location
Greece
Related Subject Headings
- Tumor Suppressor Proteins
- Tumor Cells, Cultured
- Transcription Factors
- Trans-Activators
- Reverse Transcriptase Polymerase Chain Reaction
- Prostatic Neoplasms
- Phosphoproteins
- Oncology & Carcinogenesis
- Neoplasm Staging
- Middle Aged
Citation
APA
Chicago
ICMJE
MLA
NLM
Davis, L. D., Zhang, W., Merseburger, A., Young, D., Xu, L., Rhim, J. S., … Sesterhenn, I. A. (2002). p63 expression profile in normal and malignant prostate epithelial cells. Anticancer Res, 22(6C), 3819–3825.
Davis, Leland D., Wei Zhang, Axel Merseburger, Denise Young, Linda Xu, Johng S. Rhim, Judd W. Moul, Shiv Srivastava, and Isabell A. Sesterhenn. “p63 expression profile in normal and malignant prostate epithelial cells.” Anticancer Res 22, no. 6C (2002): 3819–25.
Davis LD, Zhang W, Merseburger A, Young D, Xu L, Rhim JS, et al. p63 expression profile in normal and malignant prostate epithelial cells. Anticancer Res. 2002;22(6C):3819–25.
Davis, Leland D., et al. “p63 expression profile in normal and malignant prostate epithelial cells.” Anticancer Res, vol. 22, no. 6C, 2002, pp. 3819–25.
Davis LD, Zhang W, Merseburger A, Young D, Xu L, Rhim JS, Moul JW, Srivastava S, Sesterhenn IA. p63 expression profile in normal and malignant prostate epithelial cells. Anticancer Res. 2002;22(6C):3819–3825.
Published In
Anticancer Res
ISSN
0250-7005
Publication Date
2002
Volume
22
Issue
6C
Start / End Page
3819 / 3825
Location
Greece
Related Subject Headings
- Tumor Suppressor Proteins
- Tumor Cells, Cultured
- Transcription Factors
- Trans-Activators
- Reverse Transcriptase Polymerase Chain Reaction
- Prostatic Neoplasms
- Phosphoproteins
- Oncology & Carcinogenesis
- Neoplasm Staging
- Middle Aged