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Preoperative and operative factors to predict incontinence, impotence and stricture after radical prostatectomy.

Publication ,  Journal Article
Moul, JW; Mooneyhan, RM; Kao, T-C; McLeod, DG; Cruess, DF
Published in: Prostate Cancer Prostatic Dis
September 1998

The purpose of this study was to determine the incidence of patient-self reported post prostatectomy incontinence, impotence, bladder neck contracture or stricture, better, same or worse quality of life and willingness for same treatment again in a large group of radical prostatectomy (RP) patients and to determine if these morbidities are predictable with demographic, surgical or prostate cancer (PC) factors. Methods: A patient self-reporting questionnaire was completed and returned by 374 out of 458 eligible (81.7%) RP patients from one center, 267 (72.2%) have been operated since 1990 and all of whom were a minimum six month postoperative (75%>1 y). Questionnaire results were independently analyzed by a third party and correlated to demographic, operative, and tumor factors in an ongoing comprehensive PC database. Results: The patient self-reported incidence of post prostatectomy incontinence (any degree), impotence, and bladder neck contracture or stricture was 72.2, 87.4, and 25.9%, respectively. The reported rate of incontinence requiring protection was 39.0% and only 2.4% had persistent bladder neck contracture/stricture. Pathologic stage (continuous variable) was the only factor to significantly predict incontinence and no factor could predict impotence or bladder neck contracture/stricture in univariate analysis. No factor was predictive of morbidity by multivariate analysis. Despite incontinence and impotence significantly affecting QOL self-reporting (P=0.001, 0.001, respectively) and willingness to undergo RP again (P=0.001, 0.067, respectively), the majority of patients would choose surgery again. Conclusions: Although radical prostatectomy morbidity is common and affects patient-reported overall QOL, most patients would choose the same treatment again. Demographic, preoperative, operative, and tumor factors did not reliably predict patient-reported morbidity in this series.

Duke Scholars

Published In

Prostate Cancer Prostatic Dis

DOI

EISSN

1476-5608

Publication Date

September 1998

Volume

1

Issue

5

Start / End Page

242 / 249

Location

England

Related Subject Headings

  • Urology & Nephrology
  • 3211 Oncology and carcinogenesis
  • 3202 Clinical sciences
  • 1112 Oncology and Carcinogenesis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Moul, J. W., Mooneyhan, R. M., Kao, T.-C., McLeod, D. G., & Cruess, D. F. (1998). Preoperative and operative factors to predict incontinence, impotence and stricture after radical prostatectomy. Prostate Cancer Prostatic Dis, 1(5), 242–249. https://doi.org/10.1038/sj.pcan.4500248
Moul, J. W., R. M. Mooneyhan, T. -. C. Kao, D. G. McLeod, and D. F. Cruess. “Preoperative and operative factors to predict incontinence, impotence and stricture after radical prostatectomy.Prostate Cancer Prostatic Dis 1, no. 5 (September 1998): 242–49. https://doi.org/10.1038/sj.pcan.4500248.
Moul JW, Mooneyhan RM, Kao T-C, McLeod DG, Cruess DF. Preoperative and operative factors to predict incontinence, impotence and stricture after radical prostatectomy. Prostate Cancer Prostatic Dis. 1998 Sep;1(5):242–9.
Moul, J. W., et al. “Preoperative and operative factors to predict incontinence, impotence and stricture after radical prostatectomy.Prostate Cancer Prostatic Dis, vol. 1, no. 5, Sept. 1998, pp. 242–49. Pubmed, doi:10.1038/sj.pcan.4500248.
Moul JW, Mooneyhan RM, Kao T-C, McLeod DG, Cruess DF. Preoperative and operative factors to predict incontinence, impotence and stricture after radical prostatectomy. Prostate Cancer Prostatic Dis. 1998 Sep;1(5):242–249.

Published In

Prostate Cancer Prostatic Dis

DOI

EISSN

1476-5608

Publication Date

September 1998

Volume

1

Issue

5

Start / End Page

242 / 249

Location

England

Related Subject Headings

  • Urology & Nephrology
  • 3211 Oncology and carcinogenesis
  • 3202 Clinical sciences
  • 1112 Oncology and Carcinogenesis