Hormonal therapy options for biochemical recurrence of prostate cancer after local therapy.
Published
Journal Article (Review)
Recurrence after local prostate cancer treatment detectable only by a rise in serum prostate specific antigen (PSA) is a very common problem facing clinicians. Given that the majority of these men are relatively young and otherwise healthy, treatment of PSA-only recurrence requires approaches that not only improve survival but also preserve quality of life. For radical prostatectomy patients, a PSA-only recurrence is broadly defined as persistent or rising PSA in the postoperative period. For radiation-treated patients, the 1997 American Society for Therapeutic Radiology and Oncology guidelines specify three consecutive elevations of PSA after the post-treatment nadir PSA is achieved. Traditional hormonal therapy is the mainstay of systemic treatment for PSA-only recurrence, although nontraditional approaches such as intermittent and oral-only hormonal therapy are under study.
Full Text
Duke Authors
Cited Authors
- Moul, JW
Published Date
- 2000
Published In
Volume / Issue
- 4 / 3
Start / End Page
- 267 - 271
PubMed ID
- 11062383
Pubmed Central ID
- 11062383
International Standard Serial Number (ISSN)
- 1091-5362
Language
- eng
Conference Location
- United States