Focusing on testosterone.
Publication
, Journal Article
Moul, JW; Dreicer, R
Published in: Urology
November 2011
Since Huggins and Hodges first established testosterone as the principal androgenic hormone responsible for the growth of prostate cancer in 1941, lowering the circulating testosterone to surgical castration levels (<50 ng/dL) has been a fundamental strategy for prostate cancer therapy. Until the 1980s, surgical castration (bilateral orchiectomy) and medical castration using estrogen (diethylstilbestrol) were the primary methods of testosterone suppression. However, during the past 30 years, newer agents that lower serum testosterone even more effectively have been approved and the indications for use of these newer agents re-evaluated.
Duke Scholars
Published In
Urology
DOI
EISSN
1527-9995
Publication Date
November 2011
Volume
78
Issue
5 Suppl
Start / End Page
S476 / S477
Location
United States
Related Subject Headings
- Urology & Nephrology
- Testosterone
- Prostatic Neoplasms
- Male
- Humans
- Antineoplastic Agents, Hormonal
- 3202 Clinical sciences
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Moul, J. W., & Dreicer, R. (2011). Focusing on testosterone. Urology, 78(5 Suppl), S476–S477. https://doi.org/10.1016/j.urology.2011.06.004
Moul, Judd W., and Robert Dreicer. “Focusing on testosterone.” Urology 78, no. 5 Suppl (November 2011): S476–77. https://doi.org/10.1016/j.urology.2011.06.004.
Moul JW, Dreicer R. Focusing on testosterone. Urology. 2011 Nov;78(5 Suppl):S476–7.
Moul, Judd W., and Robert Dreicer. “Focusing on testosterone.” Urology, vol. 78, no. 5 Suppl, Nov. 2011, pp. S476–77. Pubmed, doi:10.1016/j.urology.2011.06.004.
Moul JW, Dreicer R. Focusing on testosterone. Urology. 2011 Nov;78(5 Suppl):S476–S477.
Published In
Urology
DOI
EISSN
1527-9995
Publication Date
November 2011
Volume
78
Issue
5 Suppl
Start / End Page
S476 / S477
Location
United States
Related Subject Headings
- Urology & Nephrology
- Testosterone
- Prostatic Neoplasms
- Male
- Humans
- Antineoplastic Agents, Hormonal
- 3202 Clinical sciences
- 1103 Clinical Sciences