This study, using hierarchical linear models, examined effects of the intervention programs on first-time-full-time students' retention and college cumulative GPA, interacting with students' characteristics, e.g., demographics and college preparedness. Program effects on a three-year trend were also explored. The study results show that the intervention programs had significant effects on retention and college cumulative GPA, and worked better for the first year. Interactions between program type and students' characteristics were also discussed.