Impediments to clinical research in the United States.

Journal Article (Journal Article)

Clinical trials are essential to the evaluation of promising scientific discoveries, but they are becoming unsustainably burdensome, threatening to deprive patients and health-care providers of new therapies and new evidence to guide the use of existing treatments. Regulations are often blamed for impeding clinical research, but there are other elements of the clinical trials enterprise that also have the potential to add burdens, through either imposed requirements or incentives that do not favor clinical research (Figure 1).

Full Text

Duke Authors

Cited Authors

  • Kramer, JM; Smith, PB; Califf, RM

Published Date

  • March 2012

Published In

Volume / Issue

  • 91 / 3

Start / End Page

  • 535 - 541

PubMed ID

  • 22318614

Electronic International Standard Serial Number (EISSN)

  • 1532-6535

Digital Object Identifier (DOI)

  • 10.1038/clpt.2011.341


  • eng

Conference Location

  • United States