The use of antifungal therapy in neonatal intensive care.

Journal Article (Journal Article;Review)

Invasive fungal infections remain a significant cause of infection-related mortality and morbidity in preterm infants. Central nervous system involvement is the hallmark of neonatal candidiasis, differentiating the disease's impact on young infants from that among all other patient populations. Over the past decade, the number of antifungal agents in development has grown, but most are not labeled for use in newborns. We summarize the findings of several antifungal studies that have been completed to date, emphasizing those including infant populations. We conclude that more studies are required for antifungals to be used safely and effectively in infants.

Full Text

Duke Authors

Cited Authors

  • Testoni, D; Smith, PB; Benjamin, DK

Published Date

  • March 2012

Published In

Volume / Issue

  • 39 / 1

Start / End Page

  • 83 - 98

PubMed ID

  • 22341539

Pubmed Central ID

  • PMC3285432

Electronic International Standard Serial Number (EISSN)

  • 1557-9840

Digital Object Identifier (DOI)

  • 10.1016/j.clp.2011.12.008


  • eng

Conference Location

  • United States