F-Seq: a feature density estimator for high-throughput sequence tags.

Journal Article (Journal Article)

UNLABELLED: Tag sequencing using high-throughput sequencing technologies are now regularly employed to identify specific sequence features, such as transcription factor binding sites (ChIP-seq) or regions of open chromatin (DNase-seq). To intuitively summarize and display individual sequence data as an accurate and interpretable signal, we developed F-Seq, a software package that generates a continuous tag sequence density estimation allowing identification of biologically meaningful sites whose output can be displayed directly in the UCSC Genome Browser. AVAILABILITY: The software is written in the Java language and is available on all major computing platforms for download at http://www.genome.duke.edu/labs/furey/software/fseq.

Full Text

Duke Authors

Cited Authors

  • Boyle, AP; Guinney, J; Crawford, GE; Furey, TS

Published Date

  • November 1, 2008

Published In

Volume / Issue

  • 24 / 21

Start / End Page

  • 2537 - 2538

PubMed ID

  • 18784119

Pubmed Central ID

  • PMC2732284

Electronic International Standard Serial Number (EISSN)

  • 1367-4811

Digital Object Identifier (DOI)

  • 10.1093/bioinformatics/btn480


  • eng

Conference Location

  • England