Are outcomes of extremely preterm infants improving? Impact of Bayley assessment on outcomes.


Journal Article

OBJECTIVES: To compare 18- to 22-month cognitive scores and neurodevelopmental impairment (NDI) in 2 time periods using the National Institute of Child Health and Human Development's Neonatal Research Network assessment of extremely low birth weight infants with the Bayley Scales of Infant Development, Second Edition (Bayley II) in 2006-2007 (period 1) and using the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley III), with separate cognitive and language scores, in 2008-2011 (period 2). STUDY DESIGN: Scores were compared with bivariate analysis, and regression analyses were run to identify differences in NDI rates. RESULTS: Mean Bayley III cognitive scores were 11 points higher than mean Bayley II cognitive scores. The NDI rate was reduced by 70% (from 43% in period 1 to 13% in period 2; P < .0001). Multivariate analyses revealed that Bayley III contributed to a decreased risk of NDI by 5 definitions: cognitive score <70 and <85, cognitive or language score <70; cognitive or motor score <70, and cognitive, language, or motor score <70 (P < .001). CONCLUSION: Whether the Bayley III is overestimating cognitive performance or whether it is a more valid assessment of emerging cognitive skills than the Bayley II is uncertain. Because the Bayley III identifies significantly fewer children with disability, it is recommended that all extremely low birth weight infants be offered early intervention services at the time of discharge from the neonatal intensive care unit, and that Bayley scores be interpreted with caution.

Full Text

Cited Authors

  • Vohr, BR; Stephens, BE; Higgins, RD; Bann, CM; Hintz, SR; Das, A; Newman, JE; Peralta-Carcelen, M; Yolton, K; Dusick, AM; Evans, PW; Goldstein, RF; Ehrenkranz, RA; Pappas, A; Adams-Chapman, I; Wilson-Costello, DE; Bauer, CR; Bodnar, A; Heyne, RJ; Vaucher, YE; Dillard, RG; Acarregui, MJ; McGowan, EC; Myers, GJ; Fuller, J; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network,

Published Date

  • August 2012

Published In

Volume / Issue

  • 161 / 2

Start / End Page

  • 222 - 8.e3

PubMed ID

  • 22421261

Pubmed Central ID

  • 22421261

Electronic International Standard Serial Number (EISSN)

  • 1097-6833

Digital Object Identifier (DOI)

  • 10.1016/j.jpeds.2012.01.057


  • eng

Conference Location

  • United States