Impact of obesity on cardiovascular disease.


Journal Article (Review)

Obesity promotes a cascade of secondary pathologies including diabetes, insulin resistance, dyslipidemia, inflammation, thrombosis, hypertension, the metabolic syndrome, and OSA, which collectively heighten the risk for cardiovascular disease. Obesity may also be an independent moderator of cardiac risk apart from these comorbid conditions. Rates of obesity and cardiac disease continue to rise in a parallel and exponential manner. Because obesity is potentially one of the most modifiable mediators of cardiovascular morbidity and mortality, effective treatment and prevention interventions should have a profound and favorable impact on public health.

Full Text

Duke Authors

Cited Authors

  • Zalesin, KC; Franklin, BA; Miller, WM; Peterson, ED; McCullough, PA

Published Date

  • September 2011

Published In

Volume / Issue

  • 95 / 5

Start / End Page

  • 919 - 937

PubMed ID

  • 21855700

Pubmed Central ID

  • 21855700

Electronic International Standard Serial Number (EISSN)

  • 1557-9859

Digital Object Identifier (DOI)

  • 10.1016/j.mcna.2011.06.005


  • eng

Conference Location

  • United States