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Neonatal fungal infections: when to treat?

Publication ,  Journal Article
Hsieh, E; Smith, PB; Jacqz-Aigrain, E; Kaguelidou, F; Cohen-Wolkowiez, M; Manzoni, P; Benjamin, DK
Published in: Early Hum Dev
May 2012

Candida infections are a major cause of morbidity and mortality in neonatal intensive care units. Mortality following Candida bloodstream infections is as high as 40%, and neurodevelopmental impairment is common among survivors. Because invasive fungal infections are common and extremely difficult to diagnose, empirical treatment with antifungal therapy should be considered in high-risk, low-birth-weight infants who fail to quickly respond to empirical antibacterial treatment. Risk factors to consider when deciding to administer empirical antifungal therapy include: prior exposure to third-generation cephalosporins, extreme prematurity, and presence of central venous catheters.

Duke Scholars

Published In

Early Hum Dev

DOI

EISSN

1872-6232

Publication Date

May 2012

Volume

88 Suppl 2

Issue

Suppl 2

Start / End Page

S6 / S10

Location

Ireland

Related Subject Headings

  • Treatment Outcome
  • Risk Factors
  • Pediatrics
  • Infant, Premature, Diseases
  • Infant, Premature
  • Infant, Newborn
  • Infant
  • Humans
  • Fungemia
  • Cephalosporins
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hsieh, E., Smith, P. B., Jacqz-Aigrain, E., Kaguelidou, F., Cohen-Wolkowiez, M., Manzoni, P., & Benjamin, D. K. (2012). Neonatal fungal infections: when to treat? Early Hum Dev, 88 Suppl 2(Suppl 2), S6–S10. https://doi.org/10.1016/S0378-3782(12)70004-X
Hsieh, E., P. B. Smith, E. Jacqz-Aigrain, F. Kaguelidou, M. Cohen-Wolkowiez, P. Manzoni, and D. K. Benjamin. “Neonatal fungal infections: when to treat?Early Hum Dev 88 Suppl 2, no. Suppl 2 (May 2012): S6–10. https://doi.org/10.1016/S0378-3782(12)70004-X.
Hsieh E, Smith PB, Jacqz-Aigrain E, Kaguelidou F, Cohen-Wolkowiez M, Manzoni P, et al. Neonatal fungal infections: when to treat? Early Hum Dev. 2012 May;88 Suppl 2(Suppl 2):S6–10.
Hsieh, E., et al. “Neonatal fungal infections: when to treat?Early Hum Dev, vol. 88 Suppl 2, no. Suppl 2, May 2012, pp. S6–10. Pubmed, doi:10.1016/S0378-3782(12)70004-X.
Hsieh E, Smith PB, Jacqz-Aigrain E, Kaguelidou F, Cohen-Wolkowiez M, Manzoni P, Benjamin DK. Neonatal fungal infections: when to treat? Early Hum Dev. 2012 May;88 Suppl 2(Suppl 2):S6–S10.
Journal cover image

Published In

Early Hum Dev

DOI

EISSN

1872-6232

Publication Date

May 2012

Volume

88 Suppl 2

Issue

Suppl 2

Start / End Page

S6 / S10

Location

Ireland

Related Subject Headings

  • Treatment Outcome
  • Risk Factors
  • Pediatrics
  • Infant, Premature, Diseases
  • Infant, Premature
  • Infant, Newborn
  • Infant
  • Humans
  • Fungemia
  • Cephalosporins