Therapeutic monitoring of voriconazole in children less than three years of age: a case report and summary of voriconazole concentrations for ten children.
Journal Article (Journal Article)
Voriconazole is the treatment of choice for invasive aspergillosis and its use is increasing in pediatrics. Minimal pharmacokinetic data exist in young children. We report voriconazole concentrations for 10 children <3 years of age and pharmacokinetic parameters for 1 infant who had therapeutic drug monitoring performed. Trough concentrations were unpredictable based on dose, highlighting the need to follow values during therapy.
Full Text
Duke Authors
Cited Authors
- Doby, EH; Benjamin, DK; Blaschke, AJ; Ward, RM; Pavia, AT; Martin, PL; Driscoll, TA; Cohen-Wolkowiez, M; Moran, C
Published Date
- June 2012
Published In
Volume / Issue
- 31 / 6
Start / End Page
- 632 - 635
PubMed ID
- 22301479
Pubmed Central ID
- PMC3356483
Electronic International Standard Serial Number (EISSN)
- 1532-0987
Digital Object Identifier (DOI)
- 10.1097/INF.0b013e31824acc33
Language
- eng
Conference Location
- United States