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Therapeutic monitoring of voriconazole in children less than three years of age: a case report and summary of voriconazole concentrations for ten children.

Publication ,  Journal Article
Doby, EH; Benjamin, DK; Blaschke, AJ; Ward, RM; Pavia, AT; Martin, PL; Driscoll, TA; Cohen-Wolkowiez, M; Moran, C
Published in: Pediatr Infect Dis J
June 2012

Voriconazole is the treatment of choice for invasive aspergillosis and its use is increasing in pediatrics. Minimal pharmacokinetic data exist in young children. We report voriconazole concentrations for 10 children <3 years of age and pharmacokinetic parameters for 1 infant who had therapeutic drug monitoring performed. Trough concentrations were unpredictable based on dose, highlighting the need to follow values during therapy.

Duke Scholars

Published In

Pediatr Infect Dis J

DOI

EISSN

1532-0987

Publication Date

June 2012

Volume

31

Issue

6

Start / End Page

632 / 635

Location

United States

Related Subject Headings

  • Voriconazole
  • Triazoles
  • Pyrimidines
  • Plasma
  • Pediatrics
  • Male
  • Invasive Pulmonary Aspergillosis
  • Infant
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Doby, E. H., Benjamin, D. K., Blaschke, A. J., Ward, R. M., Pavia, A. T., Martin, P. L., … Moran, C. (2012). Therapeutic monitoring of voriconazole in children less than three years of age: a case report and summary of voriconazole concentrations for ten children. Pediatr Infect Dis J, 31(6), 632–635. https://doi.org/10.1097/INF.0b013e31824acc33
Doby, Elizabeth H., Daniel K. Benjamin, Anne J. Blaschke, Robert M. Ward, Andrew T. Pavia, Paul L. Martin, Timothy A. Driscoll, Michael Cohen-Wolkowiez, and Cassandra Moran. “Therapeutic monitoring of voriconazole in children less than three years of age: a case report and summary of voriconazole concentrations for ten children.Pediatr Infect Dis J 31, no. 6 (June 2012): 632–35. https://doi.org/10.1097/INF.0b013e31824acc33.
Doby EH, Benjamin DK, Blaschke AJ, Ward RM, Pavia AT, Martin PL, et al. Therapeutic monitoring of voriconazole in children less than three years of age: a case report and summary of voriconazole concentrations for ten children. Pediatr Infect Dis J. 2012 Jun;31(6):632–5.
Doby, Elizabeth H., et al. “Therapeutic monitoring of voriconazole in children less than three years of age: a case report and summary of voriconazole concentrations for ten children.Pediatr Infect Dis J, vol. 31, no. 6, June 2012, pp. 632–35. Pubmed, doi:10.1097/INF.0b013e31824acc33.
Doby EH, Benjamin DK, Blaschke AJ, Ward RM, Pavia AT, Martin PL, Driscoll TA, Cohen-Wolkowiez M, Moran C. Therapeutic monitoring of voriconazole in children less than three years of age: a case report and summary of voriconazole concentrations for ten children. Pediatr Infect Dis J. 2012 Jun;31(6):632–635.

Published In

Pediatr Infect Dis J

DOI

EISSN

1532-0987

Publication Date

June 2012

Volume

31

Issue

6

Start / End Page

632 / 635

Location

United States

Related Subject Headings

  • Voriconazole
  • Triazoles
  • Pyrimidines
  • Plasma
  • Pediatrics
  • Male
  • Invasive Pulmonary Aspergillosis
  • Infant
  • Humans
  • Female