Blood Pressure-Lowering Mechanisms of the DASH Dietary Pattern.

Journal Article (Academic Article)

Potential blood pressure- (BP-) lowering mechanisms of the DASH dietary pattern were measured in 20 unmedicated hypertensive adults in a controlled feeding study. At screening, participants averaged 44.3 ± 7.8 years, BMI 33.9 ± 6.6 Kg/m(2), and BP 144.2 ± 9.38/88.5 ± 6.03 mmHg. All consumed a control diet for one week, then were randomized to control or DASH for another two weeks (week one and two). With DASH, but not controls, SBP fell by 10.65 ± 12.89 (P = 0.023) and 9.60 ± 11.23 (P = 0.039) mmHg and DBP by 5.95 ± 8.01 (P = 0.069) and 8.60 ± 9.13 mmHg (P = 0.011) at the end of week one and two, respectively. Univariate regressions showed that changes in urinary sodium/potassium ratio (β = 1.99) and plasma renin activity (β = -15.78) and percent change in plasma nitrite after hyperemia were associated with SBP changes at week one (all P

Full Text

Duke Authors

Cited Authors

  • Lin, PH; Allen, JD; Li, YJ; Yu, M; Lien, LF; Svetkey, LP

Published Date

  • 2012

Published In

Volume / Issue

  • 2012 /

Start / End Page

  • 472396 -

PubMed ID

  • 22496969

International Standard Serial Number (ISSN)

  • 2090-0732

Digital Object Identifier (DOI)

  • 10.1155/2012/472396

Language

  • English