Successful treatment of disseminated cryptococcal infection in a pediatric acute lymphoblastic leukemia patient during induction.

Journal Article (Journal Article)

Disseminated cryptococcal infection is rarely reported in the setting of pediatric acute leukemia, despite the immunocompromised state of these patients. However, when present, disseminated cryptococcal infection poses treatment challenges and is associated with significant morbidity and mortality. Treatment of invasive fungal disease in a child with acute leukemia requires a delicate balance between antifungal and antineoplastic therapy. This balance is particularly important early in the course of leukemia, as both the underlying disease and overwhelming infection can be life threatening. We describe the successful management of life-threatening disseminated cryptococcosis in a child with acute lymphoblastic leukemia during induction therapy.

Full Text

Duke Authors

Cited Authors

  • Heath, JL; Yin, DE; Wechsler, DS; Turner, DA

Published Date

  • May 2012

Published In

Volume / Issue

  • 34 / 4

Start / End Page

  • e161 - e163

PubMed ID

  • 22258349

Pubmed Central ID

  • PMC4628791

Electronic International Standard Serial Number (EISSN)

  • 1536-3678

Digital Object Identifier (DOI)

  • 10.1097/MPH.0b013e318236c502


  • eng

Conference Location

  • United States