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Spirometric changes in normal children with upper respiratory infections.

Publication ,  Journal Article
Collier, AM; Pimmel, RL; Hasselblad, V; Clyde, WA; Knelson, JH; Brooks, JG
Published in: Am Rev Respir Dis
January 1978

Recent evidence that certain uncomplicated upper respiratory infections induce pulmonary function abnormalities in adults prompted a prospective study in children, in whom such infections occur more frequently. In a longitudinal study, 55 children 2.5 to 11 years of age were observed for a mean duration of 2 years. Spirometry and lung volume studies were obtained routinely every 3 months, during each upper respiratory infection, and 4 weeks after illnes, providing data for 617 "well" and 237 "illness" observations. After grouping of data by sex and age (less than 84 of greater than 84 months), each spirometric parameter was analyzed using linear regression with individual identification, height, and clinical status (normal versus upper respiratory illness) as independent variables. Adjusted mean values of forced vital capacity, 1-sec forced expiratory volume, peak expiratory flow, maximal mid-expiratory flow, and expiratory flow at 50 per cent of the forced vital capacity all decreased during upper respiratory illness. The data suggest that lower respiratory tract involvement without signs or symptoms of lower airway or alveolar disease occurs with upper respiratory illnesses of varied etiologic origin in childhood.

Duke Scholars

Published In

Am Rev Respir Dis

DOI

ISSN

0003-0805

Publication Date

January 1978

Volume

117

Issue

1

Start / End Page

47 / 53

Location

United States

Related Subject Headings

  • Vital Capacity
  • Spirometry
  • Respiratory Tract Infections
  • Pulmonary Ventilation
  • Prospective Studies
  • Male
  • Lung
  • Humans
  • Female
  • Child, Preschool
 

Citation

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Collier, A. M., Pimmel, R. L., Hasselblad, V., Clyde, W. A., Knelson, J. H., & Brooks, J. G. (1978). Spirometric changes in normal children with upper respiratory infections. Am Rev Respir Dis, 117(1), 47–53. https://doi.org/10.1164/arrd.1978.117.1.47
Collier, A. M., R. L. Pimmel, V. Hasselblad, W. A. Clyde, J. H. Knelson, and J. G. Brooks. “Spirometric changes in normal children with upper respiratory infections.Am Rev Respir Dis 117, no. 1 (January 1978): 47–53. https://doi.org/10.1164/arrd.1978.117.1.47.
Collier AM, Pimmel RL, Hasselblad V, Clyde WA, Knelson JH, Brooks JG. Spirometric changes in normal children with upper respiratory infections. Am Rev Respir Dis. 1978 Jan;117(1):47–53.
Collier, A. M., et al. “Spirometric changes in normal children with upper respiratory infections.Am Rev Respir Dis, vol. 117, no. 1, Jan. 1978, pp. 47–53. Pubmed, doi:10.1164/arrd.1978.117.1.47.
Collier AM, Pimmel RL, Hasselblad V, Clyde WA, Knelson JH, Brooks JG. Spirometric changes in normal children with upper respiratory infections. Am Rev Respir Dis. 1978 Jan;117(1):47–53.

Published In

Am Rev Respir Dis

DOI

ISSN

0003-0805

Publication Date

January 1978

Volume

117

Issue

1

Start / End Page

47 / 53

Location

United States

Related Subject Headings

  • Vital Capacity
  • Spirometry
  • Respiratory Tract Infections
  • Pulmonary Ventilation
  • Prospective Studies
  • Male
  • Lung
  • Humans
  • Female
  • Child, Preschool