Assessing uncertainty in cost-effectiveness analyses: application to a complex decision model.
Publication
, Journal Article
Parmigiani, G; Samsa, GP; Ancukiewicz, M; Lipscomb, J; Hasselblad, V; Matchar, DB
Published in: Med Decis Making
1997
A framework for quantifying uncertainty about costs, effectiveness measures, and marginal cost-effectiveness ratios in complex decision models is presented. This type of application requires special techniques because of the multiple sources of information and the model-based combination of data. The authors discuss two alternative approaches, one based on Bayesian inference and the other on resampling. While computationally intensive, these are flexible in handling complex distributional assumptions and a variety of outcome measures of interest. These concepts are illustrated using a simplified model. Then the extension to a complex decision model using the stroke-prevention policy model is described.
Duke Scholars
Published In
Med Decis Making
DOI
ISSN
0272-989X
Publication Date
1997
Volume
17
Issue
4
Start / End Page
390 / 401
Location
United States
Related Subject Headings
- Quality-Adjusted Life Years
- Models, Statistical
- Humans
- Health Policy & Services
- Health Care Costs
- Decision Support Techniques
- Cost-Benefit Analysis
- Computer Simulation
- Cerebrovascular Disorders
- Bayes Theorem
Citation
APA
Chicago
ICMJE
MLA
NLM
Parmigiani, G., Samsa, G. P., Ancukiewicz, M., Lipscomb, J., Hasselblad, V., & Matchar, D. B. (1997). Assessing uncertainty in cost-effectiveness analyses: application to a complex decision model. Med Decis Making, 17(4), 390–401. https://doi.org/10.1177/0272989X9701700404
Parmigiani, G., G. P. Samsa, M. Ancukiewicz, J. Lipscomb, V. Hasselblad, and D. B. Matchar. “Assessing uncertainty in cost-effectiveness analyses: application to a complex decision model.” Med Decis Making 17, no. 4 (1997): 390–401. https://doi.org/10.1177/0272989X9701700404.
Parmigiani G, Samsa GP, Ancukiewicz M, Lipscomb J, Hasselblad V, Matchar DB. Assessing uncertainty in cost-effectiveness analyses: application to a complex decision model. Med Decis Making. 1997;17(4):390–401.
Parmigiani, G., et al. “Assessing uncertainty in cost-effectiveness analyses: application to a complex decision model.” Med Decis Making, vol. 17, no. 4, 1997, pp. 390–401. Pubmed, doi:10.1177/0272989X9701700404.
Parmigiani G, Samsa GP, Ancukiewicz M, Lipscomb J, Hasselblad V, Matchar DB. Assessing uncertainty in cost-effectiveness analyses: application to a complex decision model. Med Decis Making. 1997;17(4):390–401.
Published In
Med Decis Making
DOI
ISSN
0272-989X
Publication Date
1997
Volume
17
Issue
4
Start / End Page
390 / 401
Location
United States
Related Subject Headings
- Quality-Adjusted Life Years
- Models, Statistical
- Humans
- Health Policy & Services
- Health Care Costs
- Decision Support Techniques
- Cost-Benefit Analysis
- Computer Simulation
- Cerebrovascular Disorders
- Bayes Theorem