Economic assessment of thrombocytopenia: CATCH Registry.

Journal Article

Thrombocytopenia is associated with increased patient risk. However, the costs of this complication are not well defined. This study assessed the impact of thrombocytopenia on in-hospital costs using results from CATCH, an observational study that examined 1988 consecutive patients receiving prolonged heparin therapy (> or =96 h). Thrombocytopenia was defined as: (group 1) an absolute reduction in platelet count to <150 x 10(9)/L; (group 2) a relative reduction in platelet count of >50% from admission levels; or (group 3) both criteria. We found that the development of thrombocytopenia was associated with significantly higher total in-hospital costs for all groups: (group 1) (difference, $8,222; 95% CI, $5,020-$11,425; P<.001); (group 2) (difference, $15,429; 95% CI, $7,472-$23,385; P<.001); and (group 3) (difference, $27,077; 95% CI, $22,901-$31,252; P<.001). However, in our adjusted model, longer lengths-of-stay and greater use of blood transfusions accounted for most incremental in-hospital cost differences.

Full Text

Duke Authors

Cited Authors

  • Eisenstein, EL; Honeycutt, EF; Anstrom, KJ; Becker, RC; Granger, CB; Rao, SV; Jolicoeur, ME; Ohman, EM; CATCH Investigators,

Published Date

  • June 2010

Published In

Volume / Issue

  • 34 / 3

Start / End Page

  • 379 - 386

PubMed ID

  • 20503623

Pubmed Central ID

  • 20503623

International Standard Serial Number (ISSN)

  • 0148-5598

Digital Object Identifier (DOI)

  • 10.1007/s10916-008-9250-9


  • eng

Conference Location

  • United States