Oculogyric crises secondary to lamotrigine overdosage.

Journal Article

We report four patients with no preexisting movement disorders who developed oculogyric crises secondary to lamotrigine toxicity and had resolution of these crises after dose reduction. Episode numbers ranged from 1-20 per day and episode duration from 2 s to several hours. Mean plasma concentration of lamotrigine at the time of oculogyric crisis was 15.5 μg/mL, with a mean dose of 16 mg/kg per day.

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Duke Authors

Kansagra, Sujay Mansukhlal
Mikati, Mohamad Abdul

Cited Authors

Veerapandiyan, A; Gallentine, WB; Winchester, SA; Baker, J; Kansagra, SM; Mikati, MA

Published Date

March 2011

Published In

Epilepsia

Volume / Issue

52 / 3

Start / End Page

e4 - e6

PubMed ID

21395567

Pubmed Central ID

21395567

Electronic International Standard Serial Number (EISSN)

1528-1167

International Standard Serial Number (ISSN)

0013-9580

Digital Object Identifier (DOI)

10.1111/j.1528-1167.2010.02967.x

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