Thermospray liquid chromatography/mass spectrometry for the analysis of L-carnitine and its short-chain acyl derivatives.

Journal Article (Journal Article)

A method utilizing thermospray high-performance liquid chromatography/mass spectrometry for the separation and direct analysis of carnitine, acetylcarnitine, and propionylcarnitine is described. On-column analysis of mixtures of the acylcarnitines with their corresponding stable, isotope-labeled analogs at nanomolar concentrations has indicated that isotope dilution assays can be applied towards the analysis of carnitine and short-chain acylcarnitines present in biological samples.

Full Text

Duke Authors

Cited Authors

  • Yergey, AL; Liberato, DJ; Millington, DS

Published Date

  • June 1984

Published In

Volume / Issue

  • 139 / 2

Start / End Page

  • 278 - 283

PubMed ID

  • 6476364

International Standard Serial Number (ISSN)

  • 0003-2697

Digital Object Identifier (DOI)

  • 10.1016/0003-2697(84)90003-4


  • eng

Conference Location

  • United States