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Clinical applications of PET in oncology.

Publication ,  Journal Article
Rohren, EM; Turkington, TG; Coleman, RE
Published in: Radiology
May 2004

Positron emission tomography (PET) provides metabolic information that has been documented to be useful in patient care. The properties of positron decay permit accurate imaging of the distribution of positron-emitting radiopharmaceuticals. The wide array of positron-emitting radiopharmaceuticals has been used to characterize multiple physiologic and pathologic states. PET is used for characterizing brain disorders such as Alzheimer disease and epilepsy and cardiac disorders such as coronary artery disease and myocardial viability. The neurologic and cardiac applications of PET are not covered in this review. The major utilization of PET clinically is in oncology and consists of imaging the distribution of fluorine 18 fluorodeoxyglucose (FDG). FDG, an analogue of glucose, accumulates in most tumors in a greater amount than it does in normal tissue. FDG PET is being used in diagnosis and follow-up of several malignancies, and the list of articles supporting its use continues to grow. In this review, the physics and instrumentation aspects of PET are described. Many of the clinical applications in oncology are mature and readily covered by third-party payers. Other applications are being used clinically but have not been as carefully evaluated in the literature, and these applications may not be covered by third-party payers. The developing applications of PET are included in this review.

Duke Scholars

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

May 2004

Volume

231

Issue

2

Start / End Page

305 / 332

Location

United States

Related Subject Headings

  • Tomography, Emission-Computed
  • Thyroid Neoplasms
  • Prognosis
  • Physics
  • Physical Phenomena
  • Nuclear Medicine & Medical Imaging
  • Neoplasms
  • Neoplasm Staging
  • Melanoma
  • Lymphoma
 

Citation

APA
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ICMJE
MLA
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Rohren, E. M., Turkington, T. G., & Coleman, R. E. (2004). Clinical applications of PET in oncology. Radiology, 231(2), 305–332. https://doi.org/10.1148/radiol.2312021185
Rohren, Eric M., Timothy G. Turkington, and R Edward Coleman. “Clinical applications of PET in oncology.Radiology 231, no. 2 (May 2004): 305–32. https://doi.org/10.1148/radiol.2312021185.
Rohren EM, Turkington TG, Coleman RE. Clinical applications of PET in oncology. Radiology. 2004 May;231(2):305–32.
Rohren, Eric M., et al. “Clinical applications of PET in oncology.Radiology, vol. 231, no. 2, May 2004, pp. 305–32. Pubmed, doi:10.1148/radiol.2312021185.
Rohren EM, Turkington TG, Coleman RE. Clinical applications of PET in oncology. Radiology. 2004 May;231(2):305–332.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

May 2004

Volume

231

Issue

2

Start / End Page

305 / 332

Location

United States

Related Subject Headings

  • Tomography, Emission-Computed
  • Thyroid Neoplasms
  • Prognosis
  • Physics
  • Physical Phenomena
  • Nuclear Medicine & Medical Imaging
  • Neoplasms
  • Neoplasm Staging
  • Melanoma
  • Lymphoma