Skip to main content

Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients.

Publication ,  Journal Article
Pierson, LM; Bacon, SL; Sherwood, A; Hinderliter, AL; Babyak, M; Gullette, ECD; Waugh, R; Blumenthal, JA
Published in: J Hypertens
February 2004

OBJECTIVE: To examine the association between the graded exercise systolic blood pressure (SBP) response and left ventricular (LV) geometric structure in patients with untreated mild hypertension. PARTICIPANTS: The study included 80 sedentary, overweight patients (43 female and 37 male) with unmedicated high normal blood pressure or stage 1-2 hypertension. METHODS: An echocardiogram was used to determine LV mass and the relative wall thickness (RWT) in relation to the chamber dimension. Participants performed a maximal graded exercise test, and the SBP was recorded at workloads of 2, 4 and 6 metabolic equivalents and at peak exercise. Separate statistical models were used to determine the influence of LV mass indexed for height(2.7) (LVMIh) and RWT on submaximal exercise SBP and peak exercise SBP, controlling for resting SBP, age, gender, ethnicity and body mass index. RESULTS: A greater RWT was associated with a higher submaximal SBP level (P = 0.038). Neither LVMIh (P = 0.989) nor the interaction of RWT and LVMIh (P = 0.787) were related to the submaximal SBP. None of the main or interaction effects of RWT and LVMIh were associated with the peak exercise SBP level. CONCLUSION: Increases in RWT were associated with higher submaximal exercise SBP responses in a sample of overweight, unmedicated hypertensives. These results suggest that RWT is an important determinant of the association between cardiac mass and exercise SBP response.

Duke Scholars

Published In

J Hypertens

DOI

ISSN

0263-6352

Publication Date

February 2004

Volume

22

Issue

2

Start / End Page

399 / 405

Location

Netherlands

Related Subject Headings

  • Systole
  • Obesity
  • Middle Aged
  • Male
  • Hypertension
  • Humans
  • Heart Ventricles
  • Female
  • Exercise
  • Echocardiography
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Pierson, L. M., Bacon, S. L., Sherwood, A., Hinderliter, A. L., Babyak, M., Gullette, E. C. D., … Blumenthal, J. A. (2004). Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients. J Hypertens, 22(2), 399–405. https://doi.org/10.1097/00004872-200402000-00026
Pierson, Lee M., Simon L. Bacon, Andrew Sherwood, Alan L. Hinderliter, Michael Babyak, Elizabeth C. D. Gullette, Robert Waugh, and James A. Blumenthal. “Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients.J Hypertens 22, no. 2 (February 2004): 399–405. https://doi.org/10.1097/00004872-200402000-00026.
Pierson LM, Bacon SL, Sherwood A, Hinderliter AL, Babyak M, Gullette ECD, et al. Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients. J Hypertens. 2004 Feb;22(2):399–405.
Pierson, Lee M., et al. “Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients.J Hypertens, vol. 22, no. 2, Feb. 2004, pp. 399–405. Pubmed, doi:10.1097/00004872-200402000-00026.
Pierson LM, Bacon SL, Sherwood A, Hinderliter AL, Babyak M, Gullette ECD, Waugh R, Blumenthal JA. Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients. J Hypertens. 2004 Feb;22(2):399–405.

Published In

J Hypertens

DOI

ISSN

0263-6352

Publication Date

February 2004

Volume

22

Issue

2

Start / End Page

399 / 405

Location

Netherlands

Related Subject Headings

  • Systole
  • Obesity
  • Middle Aged
  • Male
  • Hypertension
  • Humans
  • Heart Ventricles
  • Female
  • Exercise
  • Echocardiography