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Hostility, social support, and adrenergic receptor responsiveness among African-American and white men and women.

Publication ,  Journal Article
Hughes, JW; Sherwood, A; Blumenthal, JA; Suarez, EC; Hinderliter, AL
Published in: Psychosom Med
2003

OBJECTIVE: We examined the relationship between beta-adrenergic receptor responsiveness and hostility and social support in African American and white men and women. METHODS: The participants were 149 men and women, aged 25 to 45 years with SBP < 160 and DBP < 105. Hostility and social support were assessed with standardized self-report measures. An isoproterenol challenge was used to evaluate beta-adrenergic receptor responsiveness, and a phenylephrine challenge was used to evaluate alpha-adrenergic receptor responsiveness. RESULTS: Hostility and social support were unrelated to alpha-adrenergic receptor responsiveness. Hostility and satisfaction with perceived social support predicted beta-adrenergic receptor responsiveness in multiple linear regression analyses controlling for race, gender, age, SBP, and resting heart rate. High hostility was associated with reduced cardiac beta-adrenergic receptor function among both white and African American men. Low levels of satisfaction with social support were associated with reduced cardiac beta-adrenergic receptor responsiveness among men and women. Hostility and satisfaction with social support shared some variance in models predicting beta-adrenergic receptor responsiveness. CONCLUSIONS: Reduced beta-adrenergic receptor responsiveness is associated with higher levels of hostility among men, and is associated with lower levels of satisfaction with social support among men and women. Impaired beta-adrenergic receptor function, which is a common characteristic of cardiovascular disease, may be a marker of increased cardiovascular disease risk among individuals high in hostility and low in social support.

Duke Scholars

Published In

Psychosom Med

DOI

EISSN

1534-7796

Publication Date

2003

Volume

65

Issue

4

Start / End Page

582 / 587

Location

United States

Related Subject Headings

  • Women
  • White People
  • Surveys and Questionnaires
  • Social Support
  • Receptors, Adrenergic, beta
  • Receptors, Adrenergic, alpha
  • Psychiatry
  • Phenylephrine
  • Personal Satisfaction
  • Middle Aged
 

Citation

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ICMJE
MLA
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Hughes, J. W., Sherwood, A., Blumenthal, J. A., Suarez, E. C., & Hinderliter, A. L. (2003). Hostility, social support, and adrenergic receptor responsiveness among African-American and white men and women. Psychosom Med, 65(4), 582–587. https://doi.org/10.1097/01.psy.0000041546.04128.43
Hughes, Joel W., Andrew Sherwood, James A. Blumenthal, Edward C. Suarez, and Alan L. Hinderliter. “Hostility, social support, and adrenergic receptor responsiveness among African-American and white men and women.Psychosom Med 65, no. 4 (2003): 582–87. https://doi.org/10.1097/01.psy.0000041546.04128.43.
Hughes JW, Sherwood A, Blumenthal JA, Suarez EC, Hinderliter AL. Hostility, social support, and adrenergic receptor responsiveness among African-American and white men and women. Psychosom Med. 2003;65(4):582–7.
Hughes, Joel W., et al. “Hostility, social support, and adrenergic receptor responsiveness among African-American and white men and women.Psychosom Med, vol. 65, no. 4, 2003, pp. 582–87. Pubmed, doi:10.1097/01.psy.0000041546.04128.43.
Hughes JW, Sherwood A, Blumenthal JA, Suarez EC, Hinderliter AL. Hostility, social support, and adrenergic receptor responsiveness among African-American and white men and women. Psychosom Med. 2003;65(4):582–587.

Published In

Psychosom Med

DOI

EISSN

1534-7796

Publication Date

2003

Volume

65

Issue

4

Start / End Page

582 / 587

Location

United States

Related Subject Headings

  • Women
  • White People
  • Surveys and Questionnaires
  • Social Support
  • Receptors, Adrenergic, beta
  • Receptors, Adrenergic, alpha
  • Psychiatry
  • Phenylephrine
  • Personal Satisfaction
  • Middle Aged