M-HIFU inhibits tumor growth, suppresses STAT3 activity and enhances tumor specific immunity in a transplant tumor model of prostate cancer.

In this study, we explored the use of mechanical high intensity focused ultrasound (M-HIFU) as a neo-adjuvant therapy prior to surgical resection of the primary tumor. We also investigated the role of signal transducer and activator of transcription 3 (STAT3) in M-HIFU elicited anti-tumor immune response using a transplant tumor model of prostate cancer.

Full Text

Duke Authors

Cited Authors

  • Huang, X; Yuan, F; Liang, M; Lo, HW; Shinohara, ML; Robertson, C; Zhong, P

Published Date

  • 2012

Published In

Volume / Issue

  • 7 / 7

Start / End Page

  • e41632 -

PubMed ID

  • 22911830

Electronic International Standard Serial Number (EISSN)

  • 1932-6203

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0041632

Language

  • eng

Citation Source

  • PubMed