Are sulfonylureas passé?
Publication
, Journal Article
Green, JB; Feinglos, MN
Published in: Curr Diab Rep
November 2006
Sulfonylureas and similarly acting rapid insulin secretagogues have long been available to manage type 2 diabetes. These agents have a well understood mechanism of action and are in large part well tolerated. However, sulfonylurea therapy is unlikely to sustain adequate long-term glycemic control and has potential side effects, including hypoglycemia and weight gain. Additional concerns exist regarding detrimental effects of certain sulfonylureas on ischemic preconditioning and cardiac outcomes. Fortunately, newer agents such as glimepiride appear less likely to adversely affect the myocardium. These agents can often be used successfully as one component of combination therapy for diabetes management.
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Published In
Curr Diab Rep
DOI
ISSN
1534-4827
Publication Date
November 2006
Volume
6
Issue
5
Start / End Page
373 / 377
Location
United States
Related Subject Headings
- Weight Gain
- Sulfonylurea Compounds
- Hypoglycemic Agents
- Humans
- Endocrinology & Metabolism
- Diabetes Mellitus, Type 2
- 3210 Nutrition and dietetics
- 3202 Clinical sciences
- 1117 Public Health and Health Services
- 1111 Nutrition and Dietetics
Citation
APA
Chicago
ICMJE
MLA
NLM
Green, J. B., & Feinglos, M. N. (2006). Are sulfonylureas passé? Curr Diab Rep, 6(5), 373–377. https://doi.org/10.1007/s11892-006-0008-9
Green, Jennifer B., and Mark N. Feinglos. “Are sulfonylureas passé?” Curr Diab Rep 6, no. 5 (November 2006): 373–77. https://doi.org/10.1007/s11892-006-0008-9.
Green JB, Feinglos MN. Are sulfonylureas passé? Curr Diab Rep. 2006 Nov;6(5):373–7.
Green, Jennifer B., and Mark N. Feinglos. “Are sulfonylureas passé?” Curr Diab Rep, vol. 6, no. 5, Nov. 2006, pp. 373–77. Pubmed, doi:10.1007/s11892-006-0008-9.
Green JB, Feinglos MN. Are sulfonylureas passé? Curr Diab Rep. 2006 Nov;6(5):373–377.
Published In
Curr Diab Rep
DOI
ISSN
1534-4827
Publication Date
November 2006
Volume
6
Issue
5
Start / End Page
373 / 377
Location
United States
Related Subject Headings
- Weight Gain
- Sulfonylurea Compounds
- Hypoglycemic Agents
- Humans
- Endocrinology & Metabolism
- Diabetes Mellitus, Type 2
- 3210 Nutrition and dietetics
- 3202 Clinical sciences
- 1117 Public Health and Health Services
- 1111 Nutrition and Dietetics