Unirhinal olfactory function in schizophrenia patients and first-degree relatives.

Published

Journal Article

Previous studies report birhinal impairments in odor identification in patients with schizophrenia and their family members. The authors employed unirhinal odor identification and detection threshold sensitivity tests in schizophrenia patients, healthy first-degree family members, and healthy comparison subjects. Patients and family members showed deficits in odor identification performance in both nostrils. Odor detection thresholds differed only between patients and healthy comparison subjects. Comparable odor identification deficits in both patients and healthy family members suggest that odor identification measures may serve as a sensitive endophenotypic vulnerability marker and that unirhinal olfactory measures are as precise, if not more so, than birhinal performance measures.

Full Text

Duke Authors

Cited Authors

  • Roalf, DR; Turetsky, BI; Owzar, K; Balderston, CC; Johnson, SC; Brensinger, CM; Gur, RE; Siegel, SJ; Moberg, PJ

Published Date

  • January 2006

Published In

Volume / Issue

  • 18 / 3

Start / End Page

  • 389 - 396

PubMed ID

  • 16963589

Pubmed Central ID

  • 16963589

Electronic International Standard Serial Number (EISSN)

  • 1545-7222

International Standard Serial Number (ISSN)

  • 0895-0172

Digital Object Identifier (DOI)

  • 10.1176/jnp.2006.18.3.389

Language

  • eng