Hematopoietic cell infusion for the treatment of nuclear disaster victims: new data from the Chernobyl accident.

Published

Journal Article

PURPOSE: To present previously unavailable data on the use of stem cell administration to aid recovery of victims of the Chernobyl disaster. On 26 April 1986, an accident at Unit 4 of the Chernobyl Nuclear Power Plant took place during the planned test of one of the safety systems. The diagnosis of acute radiation syndrome (ARS) was confirmed in 134 individuals exposed to high levels of radiation. There were nine patients heretofore unreported in the scientific literature who underwent intraosseous injections of allogeneic bone marrow cells in Kyiv. CONCLUSIONS: Transplantation was associated with significantly shortened time to recovery of granulocyte and platelet counts in these patients. While current guidelines would certainly include the use of cytokines, these data provide an indication of the effectiveness of stem cell transplant to treat victims of radiation exposure.

Full Text

Duke Authors

Cited Authors

  • Klymenko, SV; Belyi, DA; Ross, JR; Owzar, K; Jiang, C; Li, Z; N Minchenko, J; N Kovalenko, A; Bebeshko, VG; J Chao, N

Published Date

  • August 2011

Published In

Volume / Issue

  • 87 / 8

Start / End Page

  • 846 - 850

PubMed ID

  • 21406047

Pubmed Central ID

  • 21406047

Electronic International Standard Serial Number (EISSN)

  • 1362-3095

Digital Object Identifier (DOI)

  • 10.3109/09553002.2011.560995

Language

  • eng

Conference Location

  • England