Primary meningeal rhabdomyosarcoma.

Published

Journal Article

Primary meningeal rhabdomyosarcoma is a rare primary brain malignancy, with scant case reports. While most reports of primary intracranial rhabdomyosarcoma occur in pediatric patients, a handful of cases in adult patients have been reported in the medical literature. We report the case of a 44-year-old male who developed primary meningeal rhabdomyosarcoma. After developing episodes of right lower extremity weakness, word finding difficulty, and headaches, a brain magnetic resonance imaging (MRI) demonstrated a vertex lesion with radiographic appearance of a meningeal-derived tumor. Subtotal surgical resection was performed due to sagittal sinus invasion and initial pathology was interpreted as an anaplastic meningioma. Re-review of pathology demonstrated rhabdomyosarcoma negative for alveolar translocation t(2;13). Staging studies revealed no evidence of disseminated disease. He was treated with stereotactic radiotherapy with concurrent temozolamide to be followed by vincristine, actinomycin-D, and cyclophosphamide (VAC) systemic therapy.

Full Text

Duke Authors

Cited Authors

  • Palta, M; Riedel, RF; Vredenburgh, JJ; Cummings, TJ; Green, S; Chang, Z; Kirkpatrick, JP

Published Date

  • 2011

Published In

Volume / Issue

  • 2011 /

Start / End Page

  • 312802 -

PubMed ID

  • 21772793

Pubmed Central ID

  • 21772793

Electronic International Standard Serial Number (EISSN)

  • 1369-1643

Digital Object Identifier (DOI)

  • 10.1155/2011/312802

Language

  • eng

Conference Location

  • Egypt