Carcinoma of the urethra: radiation oncology.


Journal Article

Urethral cancer is a rare but aggressive neoplasm. Early-stage distal lesions can be successfully treated with a single modality. Results for definitive radiotherapy using either or both external beam radiation therapy and brachytherapy have shown excellent cure rates in men and women. The primary advantage of radiotherapy is organ preservation. Advanced tumors, however, have poor outcomes with single modality treatment. Results have been improved using a combination of radiotherapy and chemotherapy, chiefly 5-fluorouracil and mitomycin C. Although literature is limited to case reports because of the rarity of the disease, the markedly improved results compared with older results of surgery with or without radiation warrant consideration.

Full Text

Duke Authors

Cited Authors

  • Koontz, BF; Lee, WR

Published Date

  • August 2010

Published In

Volume / Issue

  • 37 / 3

Start / End Page

  • 459 - 466

PubMed ID

  • 20674700

Pubmed Central ID

  • 20674700

Electronic International Standard Serial Number (EISSN)

  • 1558-318X

Digital Object Identifier (DOI)

  • 10.1016/j.ucl.2010.04.007


  • eng

Conference Location

  • United States