External beam radiation therapy for clinically localized prostate cancer: when and how we optimize with concurrent hormonal deprivation.
Publication
, Journal Article
Koontz, BF; Lee, WR
Published in: Arch Esp Urol
October 2011
Androgen deprivation plays a major role in the treatment of prostate cancer.Preclinical studies have shown that androgen deprivation provides both an independent cytotoxic effect and radiosensitization on prostate tumors. For men with non-metastatic prostate cancer, the addition of androgen deprivation to radiotherapy has been shown to improve survival for intermediate and high risk disease compared to radiation alone.This review discusses the clinical trial data regarding combination of androgen deprivation and radiation and provides recommendations for its use in men undergoing radiotherapy for localized prostate cancer.
Duke Scholars
Published In
Arch Esp Urol
EISSN
1576-8260
Publication Date
October 2011
Volume
64
Issue
8
Start / End Page
858 / 864
Location
Spain
Related Subject Headings
- Urology & Nephrology
- Treatment Outcome
- Risk
- Randomized Controlled Trials as Topic
- Radiotherapy, High-Energy
- Prostatic Neoplasms
- Neoplasms, Hormone-Dependent
- Neoadjuvant Therapy
- Multicenter Studies as Topic
- Male
Citation
APA
Chicago
ICMJE
MLA
NLM
Koontz, B. F., & Lee, W. R. (2011). External beam radiation therapy for clinically localized prostate cancer: when and how we optimize with concurrent hormonal deprivation. Arch Esp Urol, 64(8), 858–864.
Koontz, Bridget F., and W Robert Lee. “External beam radiation therapy for clinically localized prostate cancer: when and how we optimize with concurrent hormonal deprivation.” Arch Esp Urol 64, no. 8 (October 2011): 858–64.
Koontz BF, Lee WR. External beam radiation therapy for clinically localized prostate cancer: when and how we optimize with concurrent hormonal deprivation. Arch Esp Urol. 2011 Oct;64(8):858–64.
Koontz, Bridget F., and W. Robert Lee. “External beam radiation therapy for clinically localized prostate cancer: when and how we optimize with concurrent hormonal deprivation.” Arch Esp Urol, vol. 64, no. 8, Oct. 2011, pp. 858–64.
Koontz BF, Lee WR. External beam radiation therapy for clinically localized prostate cancer: when and how we optimize with concurrent hormonal deprivation. Arch Esp Urol. 2011 Oct;64(8):858–864.
Published In
Arch Esp Urol
EISSN
1576-8260
Publication Date
October 2011
Volume
64
Issue
8
Start / End Page
858 / 864
Location
Spain
Related Subject Headings
- Urology & Nephrology
- Treatment Outcome
- Risk
- Randomized Controlled Trials as Topic
- Radiotherapy, High-Energy
- Prostatic Neoplasms
- Neoplasms, Hormone-Dependent
- Neoadjuvant Therapy
- Multicenter Studies as Topic
- Male