Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse.

Journal Article (Journal Article)

From a screen of small molecule libraries to identify potential therapeutics for psychostimulant abuse, 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones were shown to be isoform-selective PKC-zeta inhibitors.

Full Text

Duke Authors

Cited Authors

  • Yuan, L; Seo, J-S; Kang, NS; Keinan, S; Steele, SE; Michelotti, GA; Wetsel, WC; Beratan, DN; Gong, Y-D; Lee, TH; Hong, J

Published Date

  • September 2009

Published In

Volume / Issue

  • 5 / 9

Start / End Page

  • 927 - 930

PubMed ID

  • 19668856

Pubmed Central ID

  • PMC2747283

Electronic International Standard Serial Number (EISSN)

  • 1742-2051

Digital Object Identifier (DOI)

  • 10.1039/b903036k


  • eng

Conference Location

  • England