Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen.

Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't

In mice with Col9a1 gene inactivation (Col9a1(-/-)), osteoarthritis (OA) and intervertebral disc degeneration develop prematurely. The aim of this study was to investigate Col9a1(-/-) mice for functional and symptomatic changes that may be associated with these pathologies.

Full Text

Duke Authors

Cited Authors

  • Allen, KD; Griffin, TM; Rodriguiz, RM; Wetsel, WC; Kraus, VB; Huebner, JL; Boyd, LM; Setton, LA

Published Date

  • September 2009

Published In

Volume / Issue

  • 60 / 9

Start / End Page

  • 2684 - 2693

PubMed ID

  • 19714629

International Standard Serial Number (ISSN)

  • 0004-3591

Digital Object Identifier (DOI)

  • 10.1002/art.24783

Language

  • eng

Citation Source

  • PubMed