Neurophenotyping genetically modified mice for social behavior.

Journal Article

Sociability in mice is a multidimensional adaptive and functional response. Due to its complexity, it is important that researchers use well-defined behavioral assays that are easily replicated with clearly defined ethograms. In the Mouse Behavioral and Neuroendocrine Analysis Core Facility at Duke University, we have developed a broad series of tests that examine different components of neonatal and adult social behaviors that include sociability, sexual behavior, aggressive and territorial responses, and maternal behaviors. While the purpose of this chapter is not to provide an exhaustive description of all mouse social tests available, we provide investigators with a description of basic procedures and considerations necessary to develop a successful social behavior testing program within their laboratories.

Full Text

Duke Authors

Cited Authors

  • Rodriguiz, RM; Colvin, JS; Wetsel, WC

Published Date

  • 2011

Published In

Volume / Issue

  • 768 /

Start / End Page

  • 343 - 363

PubMed ID

  • 21805253

Electronic International Standard Serial Number (EISSN)

  • 1940-6029

Digital Object Identifier (DOI)

  • 10.1007/978-1-61779-204-5_19

Language

  • eng

Conference Location

  • United States