Skip to main content
Journal cover image

Utility of impedance cardiography for the identification of short-term risk of clinical decompensation in stable patients with chronic heart failure.

Publication ,  Journal Article
Packer, M; Abraham, WT; Mehra, MR; Yancy, CW; Lawless, CE; Mitchell, JE; Smart, FW; Bijou, R; O'Connor, CM; Massie, BM; Pina, IL; Young, JB ...
Published in: J Am Coll Cardiol
June 6, 2006

OBJECTIVES: This study sought to assess the potential utility of impedance cardiography (ICG) in predicting clinical deterioration in ambulatory patients with heart failure (HF). BACKGROUND: Impedance cardiography uses changes in thoracic electrical impedance to estimate hemodynamic variables, but its ability to predict clinical events has not been evaluated. METHODS: We prospectively evaluated 212 stable patients with HF and a recent episode of clinical decompensation who underwent serial clinical evaluation and blinded ICG testing every 2 weeks for 26 weeks and were followed up for the occurrence of death or worsening HF requiring hospitalization or emergent care. RESULTS: During the study, 59 patients experienced 104 episodes of decompensated HF (16 deaths, 78 hospitalizations, and 10 emergency visits). Multivariate analysis identified 6 clinical and ICG variables that independently predicted an event within 14 days of assessment. These included three clinical variables (visual analog score, New York Heart Association functional class, and systolic blood pressure) and three ICG parameters (velocity index, thoracic fluid content index, and left ventricular ejection time). The three ICG parameters combined into a composite score was a powerful predictor of an event during the next 14 days (p = 0.0002). Visits with a high-risk composite score had 2.5 times greater likelihood and those with a low-risk score had a 70% lower likelihood of a near-term event compared with visits at intermediate risk. CONCLUSIONS: These results suggest that when performed at regular intervals in stable patients with HF with a recent episode of clinical decompensation, ICG can identify patients at increased near-term risk of recurrent decompensation.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Am Coll Cardiol

DOI

EISSN

1558-3597

Publication Date

June 6, 2006

Volume

47

Issue

11

Start / End Page

2245 / 2252

Location

United States

Related Subject Headings

  • Risk Assessment
  • Recurrence
  • Predictive Value of Tests
  • Middle Aged
  • Male
  • Humans
  • Heart Failure
  • Female
  • Chronic Disease
  • Cardiovascular System & Hematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Packer, M., Abraham, W. T., Mehra, M. R., Yancy, C. W., Lawless, C. E., Mitchell, J. E., … Prospective Evaluation and Identification of Cardiac Decompensation by ICG Test (PREDICT) Study Investigators and Coordinators, . (2006). Utility of impedance cardiography for the identification of short-term risk of clinical decompensation in stable patients with chronic heart failure. J Am Coll Cardiol, 47(11), 2245–2252. https://doi.org/10.1016/j.jacc.2005.12.071
Packer, Milton, William T. Abraham, Mandeep R. Mehra, Clyde W. Yancy, Christine E. Lawless, Judith E. Mitchell, Frank W. Smart, et al. “Utility of impedance cardiography for the identification of short-term risk of clinical decompensation in stable patients with chronic heart failure.J Am Coll Cardiol 47, no. 11 (June 6, 2006): 2245–52. https://doi.org/10.1016/j.jacc.2005.12.071.
Packer M, Abraham WT, Mehra MR, Yancy CW, Lawless CE, Mitchell JE, et al. Utility of impedance cardiography for the identification of short-term risk of clinical decompensation in stable patients with chronic heart failure. J Am Coll Cardiol. 2006 Jun 6;47(11):2245–52.
Packer, Milton, et al. “Utility of impedance cardiography for the identification of short-term risk of clinical decompensation in stable patients with chronic heart failure.J Am Coll Cardiol, vol. 47, no. 11, June 2006, pp. 2245–52. Pubmed, doi:10.1016/j.jacc.2005.12.071.
Packer M, Abraham WT, Mehra MR, Yancy CW, Lawless CE, Mitchell JE, Smart FW, Bijou R, O’Connor CM, Massie BM, Pina IL, Greenberg BH, Young JB, Fishbein DP, Hauptman PJ, Bourge RC, Strobeck JE, Murali S, Schocken D, Teerlink JR, Levy WC, Trupp RJ, Silver MA, Prospective Evaluation and Identification of Cardiac Decompensation by ICG Test (PREDICT) Study Investigators and Coordinators. Utility of impedance cardiography for the identification of short-term risk of clinical decompensation in stable patients with chronic heart failure. J Am Coll Cardiol. 2006 Jun 6;47(11):2245–2252.
Journal cover image

Published In

J Am Coll Cardiol

DOI

EISSN

1558-3597

Publication Date

June 6, 2006

Volume

47

Issue

11

Start / End Page

2245 / 2252

Location

United States

Related Subject Headings

  • Risk Assessment
  • Recurrence
  • Predictive Value of Tests
  • Middle Aged
  • Male
  • Humans
  • Heart Failure
  • Female
  • Chronic Disease
  • Cardiovascular System & Hematology