Coping effectively with heart failure (COPE-HF): design and rationale of a telephone-based coping skills intervention.

Journal Article (Journal Article;Multicenter Study)

BACKGROUND: Coping Effectively with Heart Failure (COPE-HF) is an ongoing randomized clinical trial funded by the National Institutes of Health to evaluate if a coping skills training (CST) intervention will result in improved health status and quality of life as well as reduced mortality and hospitalizations compared with a heart failure education (HFE) intervention. METHODS AND RESULTS: Two hundred heart failure (HF) patients recruited from the Duke University Medical Center and the University of North Carolina Hospital system will be randomized to a CST intervention (16 weekly 30-minute telephone counseling sessions including motivational interviewing and individually tailored cognitive behavioral therapy) or to an HFE intervention (16 weekly 30-minute telephone sessions including education and symptom monitoring). Primary outcomes will include postintervention effects on HF biomarkers (B-type natriuretic peptide, ejection fraction) and quality of life, as well as long-term clinical outcomes (hospitalizations and death). Secondary analyses will include an evaluation of treatment effects across subpopulations, and potential mechanisms by which CST may improve clinical outcomes. CONCLUSIONS: COPE-HF is a proof-of-concept study that should provide important insights into the health benefits of a CST intervention designed to enhance HF self-management, improve health behaviors, and reduce psychologic distress.

Full Text

Duke Authors

Cited Authors

  • Sherwood, A; O'Connor, CM; Routledge, FS; Hinderliter, AL; Watkins, LL; Babyak, MA; Koch, GG; Adams, KF; Dupree, CS; Chang, PP; Hoffman, BM; Johnson, J; Bowers, M; Johnson, KS; Blumenthal, JA

Published Date

  • March 2011

Published In

Volume / Issue

  • 17 / 3

Start / End Page

  • 201 - 207

PubMed ID

  • 21362527

Pubmed Central ID

  • PMC3073538

Electronic International Standard Serial Number (EISSN)

  • 1532-8414

Digital Object Identifier (DOI)

  • 10.1016/j.cardfail.2010.11.001


  • eng

Conference Location

  • United States