Work in progress: [18F] fluorodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain.

Journal Article (Journal Article)

Five patients who had undergone radiation therapy for cerebral tumors and whose conditions were deteriorating were examined by means of positron emission tomography (PET) with [18F] fluorodeoxyglucose. All five cases had similar clinical and computed tomographic findings. Using the PET technique the two cases of radiation necrosis were distinguished from the three recurrent tumors. In the two cases of radiation necrosis the rate of glucose utilization in the lesion was markedly reduced compared with the normal brain parenchyma. In the recurrent gliomas, however, the glucose metabolic rate was elevated. All five diagnoses were confirmed by biopsy or autopsy.

Full Text

Duke Authors

Cited Authors

  • Patronas, NJ; Di Chiro, G; Brooks, RA; DeLaPaz, RL; Kornblith, PL; Smith, BH; Rizzoli, HV; Kessler, RM; Manning, RG; Channing, M; Wolf, AP; O'Connor, CM

Published Date

  • September 1982

Published In

Volume / Issue

  • 144 / 4

Start / End Page

  • 885 - 889

PubMed ID

  • 6981123

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/radiology.144.4.6981123


  • eng

Conference Location

  • United States