Insecticide resistance and malaria vector control: the importance of fitness cost mechanisms in determining economically optimal control trajectories.

Published

Journal Article

The evolutionary dynamics of insecticide resistance in harmful arthropods has economic implications, not only for the control of agricultural pests (as has been well studied), but also for the control of disease vectors, such as malaria-transmitting Anopheles mosquitoes. Previous economic work on insecticide resistance illustrates the policy relevance of knowing whether insecticide resistance mutations involve fitness costs. Using a theoretical model, this article investigates economically optimal strategies for controlling malaria-transmitting mosquitoes when there is the potential for mosquitoes to evolve resistance to insecticides. Consistent with previous literature, we find that fitness costs are a key element in the computation of economically optimal resistance management strategies. Additionally, our models indicate that different biological mechanisms underlying these fitness costs (e.g., increased adult mortality and/or decreased fecundity) can significantly alter economically optimal resistance management strategies.

Full Text

Duke Authors

Cited Authors

  • Brown, ZS; Dickinson, KL; Kramer, RA

Published Date

  • February 2013

Published In

Volume / Issue

  • 106 / 1

Start / End Page

  • 366 - 374

PubMed ID

  • 23448053

Pubmed Central ID

  • 23448053

Electronic International Standard Serial Number (EISSN)

  • 1938-291X

International Standard Serial Number (ISSN)

  • 0022-0493

Digital Object Identifier (DOI)

  • 10.1603/ec11365

Language

  • eng