Primary treatment of nasolacrimal duct obstruction with nasolacrimal duct intubation in children younger than 4 years of age.


Journal Article

To report the outcome of nasolacrimal duct intubation as the primary treatment of congenital nasolacrimal duct obstruction (NLDO) in children younger than 4 years of age.A total of 182 eyes of 139 children receiving intubation with planned tube retention for 2 to 5 months were enrolled in a prospective, nonrandomized observational multicenter study (19 sites). Children were ages 6 months to <45 months at the time of surgery, with no previous nasolacrimal surgical procedures and had at least one of the following clinical signs of NLDO: epiphora, mucous discharge, and/or increased tear lake.Treatment success was defined as absence of epiphora, mucous discharge, and increased tear lake at the outcome visit, 1 month after tube removal. The surgical outcome was assessed in 150 eyes (82% of cohort). The proportion of eyes treated successfully was 91% (95% CI: 86%-95%). The outcome dye disappearance test was normal in 125 (86%) eyes, indeterminate in 13 (9%), and abnormal in 7 (5%) of the 145 eyes tested. Monocanalicular tubes were used in 74% of cases. The tube was removed before the planned minimum retention time of 2 months in 61 eyes (41%). For 23 eyes, the early removal was attributed to inadvertent displacement by the patient.In children 6 months to <45 months of age, nasolacrimal duct intubation in a nonrandomized and noncomparative trial was a successful primary treatment of NLDO in about 90% of cases not lost to follow-up.

Full Text

Cited Authors

  • Pediatric Eye Disease Investigator Group, ; Repka, MX; Melia, BM; Beck, RW; Atkinson, CS; Chandler, DL; Holmes, JM; Khammar, A; Morrison, D; Quinn, GE; Silbert, DI; Ticho, BH; Wallace, DK; Weakley, DR

Published Date

  • October 2008

Published In

Volume / Issue

  • 12 / 5

Start / End Page

  • 445 - 450

PubMed ID

  • 18595756

Pubmed Central ID

  • 18595756

Electronic International Standard Serial Number (EISSN)

  • 1528-3933

International Standard Serial Number (ISSN)

  • 1528-3933

Digital Object Identifier (DOI)

  • 10.1016/j.jaapos.2008.03.005


  • eng