Stereoacuity in children with anisometropic amblyopia.

Published

Journal Article

To determine factors associated with pretreatment and posttreatment stereoacuity in subjects with moderate anisometropic amblyopia.Data for subjects enrolled in seven studies conducted by the Pediatric Eye Disease Investigator Group were pooled. The sample included 633 subjects aged 3 to <18 years with anisometropic amblyopia, no heterotropia observed by cover test, and baseline amblyopic eye acuity of 20/100 or better. A subset included 248 subjects who were treated with patching or Bangerter filters and had stereoacuity testing at both the baseline and outcome examinations. Multivariate regression models identified factors associated with baseline stereoacuity and with outcome stereoacuity as measured by the Randot Preschool Stereoacuity test.Better baseline stereoacuity was associated with better baseline amblyopic eye acuity (P < 0.001), less anisometropia (P = 0.03), and anisometropia due to astigmatism alone (P < 0.001). Better outcome stereoacuity was associated with better baseline stereoacuity (P < 0.001) and better amblyopic eye acuity at outcome (P < 0.001). Among 48 subjects whose amblyopic eye visual acuity at outcome was 20/25 or better and within one line of the fellow eye, stereoacuity was worse than that of children with normal vision of the same age.In children with anisometropic amblyopia of 20/40 to 20/100 inclusive, better posttreatment stereoacuity is associated with better baseline stereoacuity and better posttreatment amblyopic eye acuity. Even if their visual acuity deficit resolves, many children with anisometropic amblyopia have stereoacuity worse than that of nonamblyopic children of the same age.

Full Text

Cited Authors

  • Wallace, DK; Lazar, EL; Melia, M; Birch, EE; Holmes, JM; Hopkins, KB; Kraker, RT; Kulp, MT; Pang, Y; Repka, MX; Tamkins, SM; Weise, KK; Pediatric Eye Disease Investigator Group,

Published Date

  • October 2011

Published In

Volume / Issue

  • 15 / 5

Start / End Page

  • 455 - 461

PubMed ID

  • 22108357

Pubmed Central ID

  • 22108357

Electronic International Standard Serial Number (EISSN)

  • 1528-3933

International Standard Serial Number (ISSN)

  • 1091-8531

Digital Object Identifier (DOI)

  • 10.1016/j.jaapos.2011.06.007

Language

  • eng