Neural basis of individual differences in impulsivity: contributions of corticolimbic circuits for behavioral arousal and control.

Published

Journal Article

The objective of the current study was to analyze the neural correlates of behavioral arousal and inhibitory control as they relate to individual differences in impulsivity via well-established functional MRI amygdala reactivity and prefrontal inhibitory control paradigms in healthy adult subjects. Impulsivity correlated positively with activity of the bilateral ventral amygdala, parahippocampal gyrus, dorsal anterior cingulate gyrus (BA 32), and bilateral caudate. Conversely, impulsivity correlated negatively with activity of the dorsal amygdala and ventral prefrontal cortex (BA 47). Together, these findings suggest that dispositional impulsivity is influenced by the functional interplay of corticolimbic behavioral arousal and control circuits.

Full Text

Duke Authors

Cited Authors

  • Brown, SM; Manuck, SB; Flory, JD; Hariri, AR

Published Date

  • May 2006

Published In

Volume / Issue

  • 6 / 2

Start / End Page

  • 239 - 245

PubMed ID

  • 16768556

Pubmed Central ID

  • 16768556

Electronic International Standard Serial Number (EISSN)

  • 1931-1516

International Standard Serial Number (ISSN)

  • 1528-3542

Digital Object Identifier (DOI)

  • 10.1037/1528-3542.6.2.239

Language

  • eng