Neural basis of individual differences in impulsivity: contributions of corticolimbic circuits for behavioral arousal and control.
Journal Article (Journal Article)
The objective of the current study was to analyze the neural correlates of behavioral arousal and inhibitory control as they relate to individual differences in impulsivity via well-established functional MRI amygdala reactivity and prefrontal inhibitory control paradigms in healthy adult subjects. Impulsivity correlated positively with activity of the bilateral ventral amygdala, parahippocampal gyrus, dorsal anterior cingulate gyrus (BA 32), and bilateral caudate. Conversely, impulsivity correlated negatively with activity of the dorsal amygdala and ventral prefrontal cortex (BA 47). Together, these findings suggest that dispositional impulsivity is influenced by the functional interplay of corticolimbic behavioral arousal and control circuits.
Full Text
Duke Authors
Cited Authors
- Brown, SM; Manuck, SB; Flory, JD; Hariri, AR
Published Date
- May 2006
Published In
Volume / Issue
- 6 / 2
Start / End Page
- 239 - 245
PubMed ID
- 16768556
Electronic International Standard Serial Number (EISSN)
- 1931-1516
International Standard Serial Number (ISSN)
- 1528-3542
Digital Object Identifier (DOI)
- 10.1037/1528-3542.6.2.239
Language
- eng