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Attention-deficit/hyperactivity disorder: perspectives from neuroimaging

Publication ,  Journal Article
Hale, TS; Hariri, AR; McCracken, JT
Published in: Mental retardation and developmental disabilities research reviews
2000

Attention-deficit/hyperactivity disorder (ADHD) is a common childhood behavioral disorder most often characterized by inattentiveness, impulsivity, and hyperactivity. Current etiologic theories suggest that ADHD stems from abnormalities in dopaminergic and possibly noradrenergic brainstem nuclei that act to regulate a cortico-striato-thalamo-cortical network, believed to be critical for executive functions and the regulation of behavioral responses such as arousal, attention, and inhibition. Noninvasive structural and functional neuroimaging techniques provide a new avenue for exploring the validity of these theories. Despite their limitations, neuroimaging studies have provided a unique and otherwise inaccessible, biological perspective of ADHD. Collectively, the studies reviewed here reveal that dysfunction in arousal, behavioral inhibition, and attention associated with ADHD may result from structural abnormalities in frontostriatal regions that in turn result in diminished activity essential for normal function.

Duke Scholars

Published In

Mental retardation and developmental disabilities research reviews

DOI

Publication Date

2000

Volume

6

Issue

3

Start / End Page

214 / 219

Location

UCLA School of Medicine, Los Angeles, California 90024, USA.

Related Subject Headings

  • Tomography, X-Ray Computed
  • Tomography, Emission-Computed, Single-Photon
  • Magnetic Resonance Imaging
  • Humans
  • Electroencephalography
  • Brain
  • Attention Deficit Disorder with Hyperactivity
 

Citation

APA
Chicago
ICMJE
MLA
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Hale, T. S., Hariri, A. R., & McCracken, J. T. (2000). Attention-deficit/hyperactivity disorder: perspectives from neuroimaging. Mental Retardation and Developmental Disabilities Research Reviews, 6(3), 214–219. https://doi.org/10.1002/1098-2779(2000)6:33.0.CO;2-M
Hale, T. S., A. R. Hariri, and J. T. McCracken. “Attention-deficit/hyperactivity disorder: perspectives from neuroimaging.” Mental Retardation and Developmental Disabilities Research Reviews 6, no. 3 (2000): 214–19. https://doi.org/10.1002/1098-2779(2000)6:33.0.CO;2-M.
Hale TS, Hariri AR, McCracken JT. Attention-deficit/hyperactivity disorder: perspectives from neuroimaging. Mental retardation and developmental disabilities research reviews. 2000;6(3):214–9.
Hale, T. S., et al. “Attention-deficit/hyperactivity disorder: perspectives from neuroimaging.” Mental Retardation and Developmental Disabilities Research Reviews, vol. 6, no. 3, 2000, pp. 214–19. Manual, doi:10.1002/1098-2779(2000)6:33.0.CO;2-M.
Hale TS, Hariri AR, McCracken JT. Attention-deficit/hyperactivity disorder: perspectives from neuroimaging. Mental retardation and developmental disabilities research reviews. 2000;6(3):214–219.

Published In

Mental retardation and developmental disabilities research reviews

DOI

Publication Date

2000

Volume

6

Issue

3

Start / End Page

214 / 219

Location

UCLA School of Medicine, Los Angeles, California 90024, USA.

Related Subject Headings

  • Tomography, X-Ray Computed
  • Tomography, Emission-Computed, Single-Photon
  • Magnetic Resonance Imaging
  • Humans
  • Electroencephalography
  • Brain
  • Attention Deficit Disorder with Hyperactivity