Integrative systems biology: an attempt to describe a simple weed.
Journal Article (Review;Journal Article)
Genome-scale studies hold great promise for revealing novel plant biology. Because of the complexity of these techniques, numerous considerations need to be made before embarking on a study. Here we focus on the Arabidopsis model system because of the wealth of available genome-scale data. Many approaches are available that provide genome-scale information regarding the state of a given organism (e.g. genomics, epigenomics, transcriptomics, proteomics, metabolomics interactomics, ionomics, phenomics, etc.). Integration of all of these types of data will be necessary for a comprehensive description of Arabidopsis. In this review we propose that 'triangulation' among transcriptomics, proteomics and metabolomics is a meaningful approach for beginning this integrative analysis and uncovering a systems level perspective of Arabidopsis biology.
Full Text
Duke Authors
Cited Authors
- Liberman, LM; Sozzani, R; Benfey, PN
Published Date
- April 2012
Published In
Volume / Issue
- 15 / 2
Start / End Page
- 162 - 167
PubMed ID
- 22277598
Pubmed Central ID
- PMC3435099
Electronic International Standard Serial Number (EISSN)
- 1879-0356
International Standard Serial Number (ISSN)
- 1369-5266
Digital Object Identifier (DOI)
- 10.1016/j.pbi.2012.01.004
Language
- eng